Name | Prostate cancer (A:m6A) |
Description | METTL3 is overexpressed in prostate cancer cell lines, together with increased m6A content. SHH-GLI signaling positively correlates with the severity of PC and METTL3 regulates the expression level of GLI1 |
Related RNA reaction | A:m6A |
Found in RNA | mRNA |
Modified Transcript | SHH-GLI1 signaling |
Mapping Technology | |
Quantification techniques | m6A quantification, MeRIP-qPCR |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
METTL3 | N6-adenosine-methyltransferase 70 kDa subunit | oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1112 | RNA mA Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway. | Jiarong Cai | Onco Targets Ther | [details] | 31806999 | 10.2147/OTT.S226796 |