Summary:

NameProstate cancer (A:m6A)
DescriptionMETTL3 is overexpressed in prostate cancer cell lines, together with increased m6A content. SHH-GLI signaling positively correlates with the severity of PC and METTL3 regulates the expression level of GLI1
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptSHH-GLI1 signaling
Mapping Technology
Quantification techniquesm6A quantification, MeRIP-qPCR

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
METTL3 N6-adenosine-methyltransferase 70 kDa subunit oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1112 RNA mA Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway. Jiarong Cai Onco Targets Ther [details] 31806999 10.2147/OTT.S226796

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