NameProstate cancer (A:m6A)
DescriptionMETTL3 is overexpressed in prostate cancer cell lines, together with increased m6A content. SHH-GLI signaling positively correlates with the severity of PC and METTL3 regulates the expression level of GLI1
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptSHH-GLI1 signaling
Mapping Technology
Quantification techniquesm6A quantification, MeRIP-qPCR

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
METTL3 N6-adenosine-methyltransferase 70 kDa subunit oncogene Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
1112 RNA mA Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway. Jiarong Cai Onco Targets Ther [details] 31806999 10.2147/OTT.S226796

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