Modomics - A Database of RNA Modifications

pm7G
The molecule is shown in a ball-and-stick representation with the following colors for atoms :
⬤ Hydrogen (H): white ⬤ Carbon (C): gray ⬤ Oxygen (O): red ⬤ Phosphorus (P): orange ⬤ Nitrogen (N): blue ⬤ Selenium (Se): gold ⬤ Sulfur (S): yellow
See the molecule on the similarity map

Summary

Full name7N-methyl-8-hydroguanosine-5'-monophosphate
Short namepm7G
MODOMICS code new2000007551G
MODOMICS code7551G
Nature of the modified residueNatural
RNAMods code7
Residue unique ID203
Found in RNAYes
Related nucleosides116
RCSB ligands

7MG

G7M


Chemical information

Sum formulaC11H14N5O8P
Type of moietynucleotide
Degeneracynot aplicable
SMILESC[n+]1c2c(nc(nc2=O)N)[n]([C@H]2[C@H](O)[C@H](O)[C@@H](COP(=O)([O-])[O-])O2)c1
logP-2.1424
TPSA196.18
Number of atoms25
Number of Hydrogen Bond Acceptors 1 (HBA1)9
Number of Hydrogen Bond Acceptors 2 (HBA2)11
Number of Hydrogen Bond Donors (HBD)3
InChIInChI=1S/C11H15N5O8P/c1-15-3-16(8-5(15)9(19)14-11(12)13-8)10-7(18)6(17)4(24-10)2-23-25(20,21)22/h3-4,6-7,10,17-18H,2H2,1H3,(H3-,12,13,19,20,21,22)/p-1/t4-,6-,7-,10-/m1/s1
InChIKeyFQJGFYBYRYRCMP-KQYNXXCUSA-M
Search the molecule in external databases ChEMBL  PubChem Compound Database  Ligand Expo  WIPO 

* Chemical properties calculated with Open Babel - O'Boyle et al. Open Babel: An open chemical toolbox. J Cheminform 3, 33 (2011) (link)

QM Data:

Dipole Magnitude [D]:54.19834649
Energy [Eh]:-1645.56745819521
HOMO [eV]:-4.0903
LUMO [eV]:1.7408
Gap [eV]:5.8311

Download QM Data:

Charges   charge.txt

Download Structures

2D   .png .mol .mol2 .sdf .pdb .smi
3D   .mol .mol2 .sdf .pdb


LC-MS Information

Monoisotopic massNone
Average mass375.231
[M+H]+ not available
Product ions not available
Normalized LC elution time * not available
LC elution order/characteristics not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

Last modification of this entry: Sept. 15, 2025