ID Card:
Protein sequence:
MGEKRNRNGKDANSQNRKKFKVSSGFLDPGTSGIYATCSRRHERQAAQELQLLFEEKFQELYGDIKEGEDESENDEKKDLSIEDQIKKELQELKGEETGKDLSSGETKKKDPLAFIDLNCECVTFCKTRKPIVPEEFVLSIMKDLADPKNMVKRTRYVQKLTPITYSCNAKMEQLIKLANLVIGPHFHDPSNVKKNYKFAVEVTRRNFNTIERMDIINQVVKLVNKEGSEFNHTVDLKNYDKLILVECFKSNIGMCVVDGDYKTKYRKYNVQQLYESKFRKDEDKSVKQ
Comments:
TAN1 is required for formation of ac4C12 in leucine and serine tRNAs. TAN1 interacts in vivo in yeast cells with RRA1 (KRE33), and, on this basis, was suggested to work as a tRNA adaptor to Kre33, which is a demonstrated catalytically active acetyltransferase. The human homolog of TAN1 is THUMPD1. THUMPD1 interacts in vivo with NAT10, the human homolog of KRE33.
Alpha Fold Predicted Structure:
Parsing response... [147194/275080]
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Protein sequence:
M
G
E
K
R
N
R
N
G
K
D
A
N
S
Q
N
R
K
K
F
K
V
S
S
G
F
L
D
P
G
T
S
G
I
Y
A
T
C
S
R
R
H
E
R
Q
A
A
Q
E
L
Q
L
L
F
E
E
K
F
Q
E
L
Y
G
D
I
K
E
G
E
D
E
S
E
N
D
E
K
K
D
L
S
I
E
D
Q
I
K
K
E
L
Q
E
L
K
G
E
E
T
G
K
D
L
S
S
G
E
T
K
K
K
D
P
L
A
F
I
D
L
N
C
E
C
V
T
F
C
K
T
R
K
P
I
V
P
E
E
F
V
L
S
I
M
K
D
L
A
D
P
K
N
M
V
K
R
T
R
Y
V
Q
K
L
T
P
I
T
Y
S
C
N
A
K
M
E
Q
L
I
K
L
A
N
L
V
I
G
P
H
F
H
D
P
S
N
V
K
K
N
Y
K
F
A
V
E
V
T
R
R
N
F
N
T
I
E
R
M
D
I
I
N
Q
V
V
K
L
V
N
K
E
G
S
E
F
N
H
T
V
D
L
K
N
Y
D
K
L
I
L
V
E
C
F
K
S
N
I
G
M
C
V
V
D
G
D
Y
K
T
K
Y
R
K
Y
N
V
Q
Q
L
Y
E
S
K
F
R
K
D
E
D
K
S
V
K
Q
50 100 150 200 250 Sequence G H T B S N
Secondary Structure Alphabet
G: 3-turn helix (310 helix) H: α-helix I: 𝝅-helix (5 - turn helix) T: Hydrogen Bonded Turn B: β-sheet S: Bend C: Coil (residues not present in any of the above conformations) N: Not assigned
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