ID Card:
Full name:
tRNA guanosine(34) transglycosylase
Synonym:
JW0396
GI:
67473024
Orf:
b0406
COG:
COG0343
UniProt:
P0A847
Alpha Fold Predicted Structure:
AF-P0A847-F1
Enzyme type:
transglycosylase
Position of modification - modification:
t :34 - Q
Protein sequence:
MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
Comments:
Reaction preQ0(b):preQ0 do not occur under physiological conditions, because normally all preQ0(b) is converted to preQ1(b) by QueF. Do not exist in S. cerevisiae, exist in other yeast (Tgt, O94460, GI20514973, SPAC1687.19c). Structure in complex with tRNA was solved for Tgt enzyme from Zymomonas mobilis (1Q2R).
Reaction
Substrate
SubstrateType
Position
(Anti)Codon
Modified (Anti)Codon
Amino Acid Change
Transcript Name
Transcript Region
Cellular Localization
References
preQ1base:preQ1
tRNA (t)
34
Alpha Fold Predicted Structure:
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Protein sequence:
M
K
F
E
L
D
T
T
D
G
R
A
R
R
G
R
L
V
F
D
R
G
V
V
E
T
P
C
F
M
P
V
G
T
Y
G
T
V
K
G
M
T
P
E
E
V
E
A
T
G
A
Q
I
I
L
G
N
T
F
H
L
W
L
R
P
G
Q
E
I
M
K
L
H
G
D
L
H
D
F
M
Q
W
K
G
P
I
L
T
D
S
G
G
F
Q
V
F
S
L
G
D
I
R
K
I
T
E
Q
G
V
H
F
R
N
P
I
N
G
D
P
I
F
L
D
P
E
K
S
M
E
I
Q
Y
D
L
G
S
D
I
V
M
I
F
D
E
C
T
P
Y
P
A
D
W
D
Y
A
K
R
S
M
E
M
S
L
R
W
A
K
R
S
R
E
R
F
D
S
L
G
N
K
N
A
L
F
G
I
I
Q
G
S
V
Y
E
D
L
R
D
I
S
V
K
G
L
V
D
I
G
F
D
G
Y
A
V
G
G
L
A
V
G
E
P
K
A
D
M
H
R
I
L
E
H
V
C
P
Q
I
P
A
D
K
P
R
Y
L
M
G
V
G
K
P
E
D
L
V
E
G
V
R
R
G
I
D
M
F
D
C
V
M
P
T
R
N
A
R
N
G
H
L
F
V
T
D
G
V
V
K
I
R
N
A
K
Y
K
S
D
T
G
P
L
D
P
E
C
D
C
Y
T
C
R
N
Y
S
R
A
Y
L
H
H
L
D
R
C
N
E
I
L
G
A
R
L
N
T
I
H
N
L
R
Y
Y
Q
R
L
M
A
G
L
R
K
A
I
E
E
G
K
L
E
S
F
V
T
D
F
Y
Q
R
Q
G
R
E
V
P
P
L
N
V
D
Secondary Structure Alphabet
G: 3-turn helix (310 helix) H: α-helix I: 𝝅-helix (5 - turn helix) T: Hydrogen Bonded Turn B: β-sheet S: Bend C: Coil (residues not present in any of the above conformations) N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
Publications:
Title
Authors
Journal
Details
PubMed Id DOI
New function of vitamin B12: cobamide-dependent reduction of epoxyqueuosine to queuosine in tRNAs of Escherichia coli and Salmonella typhimurium.
Frey B, McCloskey J, Kersten W, Kersten H
J Bacteriol
[details]
3129401
-
Links: