ID Card:
Full name:
Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase
Synonym:
aFib, PH0052, Fibrillarin-like
GI:
14590005
COG:
COG1889
UniProt:
O57811
Structures:
|
1G8A |
Alpha Fold Predicted Structure:
AF-O57811-F1
Complex:
C/D RNP
Enzyme type:
methyltransferase
Position of modification - modification:
l :many - Xm s :many - Xm
PDB Structures:
1G8A
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1G8A
Structure Description:
Abstract of the PDB Structure's related Publication:
Download RCSB-PDB Structures:
Protein sequence:
MVEVKKHKFPGVYTVIDDDGSERIATKNLVPGQRVYGERVIKWEGEEYRIWNPNRSKLGAAIMNGLKNFPIKPGKSVLYLGIASGTTASHVSDIVGWEGKIFGIEFSPRVLRELVPIVEERRNIVPILGDATKPEEYRALVPKVDVIFEDVAQPTQAKILIDNAEVYLKRGGYGMIAVKSRSIDVTKEPEQVFREVERELSEYFEVIERLNLEPYEKDHALFVVRKT
Comments:
Homologue of yeast Nop1 protein and human fibrillarin. A catalytic subunit of C/D RNP complex, which in Archaea is composed of FlpA (fibrillarin), L7Ae and Nop56/58 proteins.
Reaction
Substrate
SubstrateType
Position
(Anti)Codon
Modified (Anti)Codon
Amino Acid Change
Transcript Name
Transcript Region
Cellular Localization
References
N:Nm
undefined RNA ()
3'end
N:Nm
undefined RNA ()
3'end
Alpha Fold Predicted Structure:
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Protein sequence:
M
V
E
V
K
K
H
K
F
P
G
V
Y
T
V
I
D
D
D
G
S
E
R
I
A
T
K
N
L
V
P
G
Q
R
V
Y
G
E
R
V
I
K
W
E
G
E
E
Y
R
I
W
N
P
N
R
S
K
L
G
A
A
I
M
N
G
L
K
N
F
P
I
K
P
G
K
S
V
L
Y
L
G
I
A
S
G
T
T
A
S
H
V
S
D
I
V
G
W
E
G
K
I
F
G
I
E
F
S
P
R
V
L
R
E
L
V
P
I
V
E
E
R
R
N
I
V
P
I
L
G
D
A
T
K
P
E
E
Y
R
A
L
V
P
K
V
D
V
I
F
E
D
V
A
Q
P
T
Q
A
K
I
L
I
D
N
A
E
V
Y
L
K
R
G
G
Y
G
M
I
A
V
K
S
R
S
I
D
V
T
K
E
P
E
Q
V
F
R
E
V
E
R
E
L
S
E
Y
F
E
V
I
E
R
L
N
L
E
P
Y
E
K
D
H
A
L
F
V
V
R
K
T
Secondary Structure Alphabet
G: 3-turn helix (310 helix) H: α-helix I: 𝝅-helix (5 - turn helix) T: Hydrogen Bonded Turn B: β-sheet S: Bend C: Coil (residues not present in any of the above conformations) N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
Publications:
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