Modomics - A Database of RNA Modifications

ID Card:

Full name: tRNA 2-thiouridine synthesizing protein E
Synonym: yccK
GI: 90111197
COG: COG2920
UniProt: P0AB18
Structures: | |
Alpha Fold Predicted Structure: AF-P0AB18-F1
Enzyme type: sulfurtransferase



Protein sequence:

MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGISLSPEHWEVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI

Comments:

TusE binds TusBCD complex and stimulates sulfur transfer from TusA to TusD. TusE also interacts with a MnmA-tRNA complex. It is necessary for sulfur transfer from IscS cysteine desulfurase to MnmA protein which participates in mnm5s2U synthesis at tRNA wobble positions.





Alpha Fold Predicted Structure:




Processing file... [109514/109514]


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Protein sequence:

M L I F E G K E I E T D T E G Y L K E S S Q W S E P L A V V I A E N E G I S L S P E H W E V V R F V R D F Y L E F N T S P A I R M L V K A M A N K F G E E K G N S R Y L Y R L F P K G P A K Q A T K I A G L P K P V K C I
102030405060708090100MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGISLSPEHWEVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCISequenceGHTBSN

Enter the variants

Position

Original

Variant

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-P0AB18-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-P0AB18-F1.cif  
DSSP Secondary Structures   P0AB18.dssp  





Publications:

Links:

_PubMed_
_EcoCyc_