ID Card:
| Full name: |
tRNA (guanine(6)-N2)-methyltransferase |
| Synonym: |
Trm14, MJ0438 |
| GI: |
15668614
|
| COG: |
COG0116 |
| UniProt: |
Q57880 |
| Alpha Fold Predicted Structure: |
AF-Q57880-F1 |
| Enzyme type: |
methyltransferase |
| Position of modification - modification: |
t:6 - m2G
|
Protein sequence:
MDYYVTLSPGLEKISKNEIESFGGKIKEIRENKGRIFFSGDLKLIPKINYLSRTIERMNILLHREEIPNIALDDIYKRVYNIDWTEWIKENQSFAIRPLRAGEHNFTSIDIGRVAGEAVIKSYQRDKNIRLKVNLDEPDVIVRVEVIFDELIVGIDTTGDIALDKRGYRVFNHPAHLNATIASSLVYLSDWKDDEMLLDPMCGSGTIPIEGALMKRNIPPGKFRENKYGFKFIDIFGYELLDKIKKEIVENKNIYKIIGLDKNQKYLDGAKDNAKNAEVLDTIEFICGDATKLHEKFNESDVIIANPPYGIRIGSKRSVKKLYDEFLSSAKEIMHGSSRLIVITAEDKMFKDAIAKNNFEVKEEFNVMFGGLMTRVFYLTL
Comments:
Distant homologs of Trm14 were also identified in eykaryota known to possess the m2G6 tRNA modification
Alpha Fold Predicted Structure:
Clear Selection and Reset Camera
Protein sequence:
M
D
Y
Y
V
T
L
S
P
G
L
E
K
I
S
K
N
E
I
E
S
F
G
G
K
I
K
E
I
R
E
N
K
G
R
I
F
F
S
G
D
L
K
L
I
P
K
I
N
Y
L
S
R
T
I
E
R
M
N
I
L
L
H
R
E
E
I
P
N
I
A
L
D
D
I
Y
K
R
V
Y
N
I
D
W
T
E
W
I
K
E
N
Q
S
F
A
I
R
P
L
R
A
G
E
H
N
F
T
S
I
D
I
G
R
V
A
G
E
A
V
I
K
S
Y
Q
R
D
K
N
I
R
L
K
V
N
L
D
E
P
D
V
I
V
R
V
E
V
I
F
D
E
L
I
V
G
I
D
T
T
G
D
I
A
L
D
K
R
G
Y
R
V
F
N
H
P
A
H
L
N
A
T
I
A
S
S
L
V
Y
L
S
D
W
K
D
D
E
M
L
L
D
P
M
C
G
S
G
T
I
P
I
E
G
A
L
M
K
R
N
I
P
P
G
K
F
R
E
N
K
Y
G
F
K
F
I
D
I
F
G
Y
E
L
L
D
K
I
K
K
E
I
V
E
N
K
N
I
Y
K
I
I
G
L
D
K
N
Q
K
Y
L
D
G
A
K
D
N
A
K
N
A
E
V
L
D
T
I
E
F
I
C
G
D
A
T
K
L
H
E
K
F
N
E
S
D
V
I
I
A
N
P
P
Y
G
I
R
I
G
S
K
R
S
V
K
K
L
Y
D
E
F
L
S
S
A
K
E
I
M
H
G
S
S
R
L
I
V
I
T
A
E
D
K
M
F
K
D
A
I
A
K
N
N
F
E
V
K
E
E
F
N
V
M
F
G
G
L
M
T
R
V
F
Y
L
T
L
Secondary Structure Alphabet
- G: 3-turn helix (310helix)
- H: α-helix
- I: 𝝅-helix (5 - turn helix)
- T: Hydrogen Bonded Turn
- B: β-sheet
- S: Bend
- C: Coil (residues not present in any of the above conformations)
- N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
Publications: