ID Card:
Full name:
YrdC-like domain-containing protein
Synonym:
smu.1377c
GI:
24379784
COG:
COG0009
UniProt:
Q8DTG7
Structures:
|
3L7V |
Alpha Fold Predicted Structure:
AF-Q8DTG7-F1
Enzyme type:
threonylcarbamoyladenosine synthetase predicted
PDB Structures:
3L7V
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3L7V
Structure Description:
Abstract of the PDB Structure's related Publication:
Members of the Sua5_YciO_YrdC protein family are found in both eukaryotes and prokaryotes and possess a conserved alpha/beta twisted open-sheet fold. The Escherichia coli protein YrdC has been shown to be involved in modification of tRNA. The crystal structure of smu.1377c, a hypothetical protein from Streptococcus mutans, has been determined to 2.25 A resolution. From structure analysis and comparison, it is shown that smu.1377c is a member of the Sua5_YciO_YrdC family and that it may play the same role as E. coli YrdC.
Download RCSB-PDB Structures:
Protein sequence:
MTKHIHWDGNLSQEGFEIVKGEGGVIVCPTKVGYIIMTSDKKGLERKFEAKKRNRNKPGVVLCGSMEELRALAQLTPEIDAFYQKHWDEDILLGCILPWKAEAYEKLKAYGDGREELMTDIRGTSCFVIKFGVAGEQIAKEMWEKEGRMVYASSANPSGKGNRGKVEGIGERIESMVDLVIEADDYVASIQPDKTIETRYEQGVMVSMVDKDGKLIPQQGADSRSVEPCPVVIRKGLDIDKIMMHLSDQFNSWNYRQGEYY
Comments:
The putative function of this protein came only from its homology to bacterial/Eukaryal/Archaeal TsaC/Sua5 homologs.
Alpha Fold Predicted Structure:
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Protein sequence:
M
T
K
H
I
H
W
D
G
N
L
S
Q
E
G
F
E
I
V
K
G
E
G
G
V
I
V
C
P
T
K
V
G
Y
I
I
M
T
S
D
K
K
G
L
E
R
K
F
E
A
K
K
R
N
R
N
K
P
G
V
V
L
C
G
S
M
E
E
L
R
A
L
A
Q
L
T
P
E
I
D
A
F
Y
Q
K
H
W
D
E
D
I
L
L
G
C
I
L
P
W
K
A
E
A
Y
E
K
L
K
A
Y
G
D
G
R
E
E
L
M
T
D
I
R
G
T
S
C
F
V
I
K
F
G
V
A
G
E
Q
I
A
K
E
M
W
E
K
E
G
R
M
V
Y
A
S
S
A
N
P
S
G
K
G
N
R
G
K
V
E
G
I
G
E
R
I
E
S
M
V
D
L
V
I
E
A
D
D
Y
V
A
S
I
Q
P
D
K
T
I
E
T
R
Y
E
Q
G
V
M
V
S
M
V
D
K
D
G
K
L
I
P
Q
Q
G
A
D
S
R
S
V
E
P
C
P
V
V
I
R
K
G
L
D
I
D
K
I
M
M
H
L
S
D
Q
F
N
S
W
N
Y
R
Q
G
E
Y
Y
Secondary Structure Alphabet
G: 3-turn helix (310 helix) H: α-helix I: 𝝅-helix (5 - turn helix) T: Hydrogen Bonded Turn B: β-sheet S: Bend C: Coil (residues not present in any of the above conformations) N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
Publications:
Title
Authors
Journal
Details
PubMed Id DOI
The structure of the hypothetical protein smu.1377c from Streptococcus mutans suggests a role in tRNA modification.
Fu TM, Liu X, Li L, Su XD
Acta Crystallogr Sect F Struct Biol Cryst Commun
[details]
20606270
-