Full name: | tRNA N6-threonylcarbamoyladenosine(37) synthesis protein |
---|---|
Synonym: | YjeE |
GI: | 16131990 |
COG: | COG0802 |
UniProt: | P0AF67 |
Alpha Fold Predicted Structure: | AF-P0AF67-F1 |
Complex: | TsaBDE |
Enzyme type: | ATPase |
Position of modification - modification: |
t:37 - t6A |
MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTFSRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFANDAICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG
This protein belongs to P-loop ATPases. It binds ATP and displays a weak ATPase activity (produce ADP). This protein tends to oligomerize in vitro. Despite TsaC (YrdC), TsaD (YgjD) and TsaB (YeaZ) are present in all bacteria, TsaE (YjeE) is absent in several unicellular and symbiotic bacteria, suggesting that some bacteria can carry out t6A synthesis in absence of YjeE. However, TsaD, TsaC, TsaE and TsaB are both necessary and sufficient for t6A biosynthesis in vitro.
Enter the variants
Position
Original
Variant
Alpha Fold Pdb Files | AF-P0AF67-F1.pdb |
Alpha Fold Pdbx/mmCIF Files | AF-P0AF67-F1.cif |
DSSP Secondary Structures | P0AF67.dssp |