Modomics - A Database of RNA Modifications

ID Card:

Full name: Killer toxin insensitivity protein 12
GI: 6322739
Orf: YKL446, YKL500
COG: COG4088
UniProt: P34253
Alpha Fold Predicted Structure: AF-P34253-F1



Protein sequence:

MPLVLFTGYPCSGKTTLAKHLVQLLQSKIDATPSLSKYSITYHSDESLGIKHSDYITSQDERKLRSEIISAVKRDLSKNKIVIVDSLNYIKGFRYQLHCEVKNLSTTFCVIQTLCPPETIFEWNKTSNPNPWEPELLNQLIQRYEEPNSSNRWDSPLFAILTPQDNITDYIDDICKVVFQTSKSAKNSGHNDPLSKGLQKPNSATVLKPASQSNFIQVLDIETSKIIKTIMNHIKSLTSIGGVSNGTRVIVSEGITDINDDGCFFVDLPIGNVVTLAQLQRLKRQFINFNKLRDIDQDRIGPLFADYLNKNLN

Comments:

One of the many protein cofactors required for an early step in synthesis of 5-methoxycarbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups present on uridines at the wobble position in tRNA. The enzyme that catalyzes this reaction is still unknown (2012).





Alpha Fold Predicted Structure:




Parsing response... [179962/290894]


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Protein sequence:

M P L V L F T G Y P C S G K T T L A K H L V Q L L Q S K I D A T P S L S K Y S I T Y H S D E S L G I K H S D Y I T S Q D E R K L R S E I I S A V K R D L S K N K I V I V D S L N Y I K G F R Y Q L H C E V K N L S T T F C V I Q T L C P P E T I F E W N K T S N P N P W E P E L L N Q L I Q R Y E E P N S S N R W D S P L F A I L T P Q D N I T D Y I D D I C K V V F Q T S K S A K N S G H N D P L S K G L Q K P N S A T V L K P A S Q S N F I Q V L D I E T S K I I K T I M N H I K S L T S I G G V S N G T R V I V S E G I T D I N D D G C F F V D L P I G N V V T L A Q L Q R L K R Q F I N F N K L R D I D Q D R I G P L F A D Y L N K N L N
50100150200250300SequenceGHTBSN

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-P34253-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-P34253-F1.cif  
DSSP Secondary Structures   P34253.dssp  





Publications:

Links:

_PubMed_