ID Card:
Full name: |
tRNA methyltransferase 10 homolog A |
Synonym: |
RG9MTD2 |
GI: |
22748659
|
UniProt: |
Q8TBZ6 |
Structures: |
|
4FMW |
|
Alpha Fold Predicted Structure: |
AF-Q8TBZ6-F1 |
Enzyme type: |
methyltransferase |
Position of modification - modification: |
t:9 - m1G
|
PDB Structures:
4FMW
Structure Description:
Title: |
Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2 |
Classification: |
TRANSFERASE |
X-Ray Diffraction |
2.0 |
0.243 |
0.219 |
0.218 |
Abstract of the PDB Structure's related Publication:
Download RCSB-PDB Structures:
Protein sequence:
MSSEMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHDRKRVRRDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKMNSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGGSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH
Comments:
Ortholog of yeast Trm10, cytoplasmic. TRMT10A deficiency accounts for abnormalities in glucose homeostasis.
Alpha Fold Predicted Structure:
Parsing response... [323140/323140]
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Protein sequence:
M
S
S
E
M
L
P
A
F
I
E
T
S
N
V
D
K
K
Q
G
I
N
E
D
Q
E
E
S
Q
K
P
R
L
G
E
G
C
E
P
I
S
K
R
Q
M
K
K
L
I
K
Q
K
Q
W
E
E
Q
R
E
L
R
K
Q
K
R
K
E
K
R
K
R
K
K
L
E
R
Q
C
Q
M
E
P
N
S
D
G
H
D
R
K
R
V
R
R
D
V
V
H
S
T
L
R
L
I
I
D
C
S
F
D
H
L
M
V
L
K
D
I
K
K
L
H
K
Q
I
Q
R
C
Y
A
E
N
R
R
A
L
H
P
V
Q
F
Y
L
T
S
H
G
G
Q
L
K
K
N
M
D
E
N
D
K
G
W
V
N
W
K
D
I
H
I
K
P
E
H
Y
S
E
L
I
K
K
E
D
L
I
Y
L
T
S
D
S
P
N
I
L
K
E
L
D
E
S
K
A
Y
V
I
G
G
L
V
D
H
N
H
H
K
G
L
T
Y
K
Q
A
S
D
Y
G
I
N
H
A
Q
L
P
L
G
N
F
V
K
M
N
S
R
K
V
L
A
V
N
H
V
F
E
I
I
L
E
Y
L
E
T
R
D
W
Q
E
A
F
F
T
I
L
P
Q
R
K
G
A
V
P
T
D
K
A
C
E
S
A
S
H
D
N
Q
S
V
R
M
E
E
G
G
S
D
S
D
S
S
E
E
E
Y
S
R
N
E
L
D
S
P
H
E
E
K
Q
D
K
E
N
H
T
E
S
T
V
N
S
L
P
H
Secondary Structure Alphabet
- G: 3-turn helix (310helix)
- H: α-helix
- I: 𝝅-helix (5 - turn helix)
- T: Hydrogen Bonded Turn
- B: β-sheet
- S: Bend
- C: Coil (residues not present in any of the above conformations)
- N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
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