ID Card:
| Full name: |
tRNA methyltransferase 10 homolog B |
| Synonym: |
RG9MTD3 |
| GI: |
117606330
|
| UniProt: |
Q6PF06 |
| Alpha Fold Predicted Structure: |
AF-Q6PF06-F1 |
| Enzyme type: |
methyltransferase |
| Position of modification - modification: |
t:9 - m1G
|
Protein sequence:
MDWKLEGSTQKVESPVLQGQEGILEETGEDGLPEGFQLLQIDAEGECQEGEILATGSTAWCSKNVQRKQRHWEKIVAAKKSKRKQEKERRKANRAENPGICPQHSKRFLRALTKDKLLEAKHSGPRLCIDLSMTHYMSKKELSRLAGQIRRLYGSNKKADRPFWICLTGFTTDSPLYEECVRMNDGFSSYLLDITEEDCFSLFPLETLVYLTPDSEHALEDVDLNKVYILGGLVDESIQKKVTFQKAREYSVKTARLPIQEYMVRNQNGKNYHSEILAINQVFDILSTYLETHNWPEALKKGVSSGKGYILRNSVE
Comments:
Ortholog of yeast Trm10, cytoplasmic.
| Reaction |
Substrate |
SubstrateType |
Position |
(Anti)Codon |
Modified (Anti)Codon |
Amino Acid Change |
Transcript Name |
Transcript Region |
Cellular Localization |
References |
|
G:m1G
|
tRNA (t) |
|
9 |
|
|
|
|
|
|
23042678
|
Alpha Fold Predicted Structure:
Clear Selection and Reset Camera
Protein sequence:
M
D
W
K
L
E
G
S
T
Q
K
V
E
S
P
V
L
Q
G
Q
E
G
I
L
E
E
T
G
E
D
G
L
P
E
G
F
Q
L
L
Q
I
D
A
E
G
E
C
Q
E
G
E
I
L
A
T
G
S
T
A
W
C
S
K
N
V
Q
R
K
Q
R
H
W
E
K
I
V
A
A
K
K
S
K
R
K
Q
E
K
E
R
R
K
A
N
R
A
E
N
P
G
I
C
P
Q
H
S
K
R
F
L
R
A
L
T
K
D
K
L
L
E
A
K
H
S
G
P
R
L
C
I
D
L
S
M
T
H
Y
M
S
K
K
E
L
S
R
L
A
G
Q
I
R
R
L
Y
G
S
N
K
K
A
D
R
P
F
W
I
C
L
T
G
F
T
T
D
S
P
L
Y
E
E
C
V
R
M
N
D
G
F
S
S
Y
L
L
D
I
T
E
E
D
C
F
S
L
F
P
L
E
T
L
V
Y
L
T
P
D
S
E
H
A
L
E
D
V
D
L
N
K
V
Y
I
L
G
G
L
V
D
E
S
I
Q
K
K
V
T
F
Q
K
A
R
E
Y
S
V
K
T
A
R
L
P
I
Q
E
Y
M
V
R
N
Q
N
G
K
N
Y
H
S
E
I
L
A
I
N
Q
V
F
D
I
L
S
T
Y
L
E
T
H
N
W
P
E
A
L
K
K
G
V
S
S
G
K
G
Y
I
L
R
N
S
V
E
Secondary Structure Alphabet
- G: 3-turn helix (310helix)
- H: α-helix
- I: 𝝅-helix (5 - turn helix)
- T: Hydrogen Bonded Turn
- B: β-sheet
- S: Bend
- C: Coil (residues not present in any of the above conformations)
- N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| A subcomplex of human mitochondrial RNase P is a bifunctional methyltransferase--extensive moonlighting in mitochondrial tRNA biogenesis. |
Vilardo E, Nachbagauer C, Buzet A, Taschner A, Holzmann J, Rossmanith W... |
Nucleic Acids Res |
[details]
|
23042678
|
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|