Modomics - A Database of RNA Modifications

ID Card:

Full name: heterogeneous nuclear ribonucleoprotein A2/B1
Synonym: HNRPA2B1
GI: 133257
UniProt: P22626
Structures: | 1X4B | 5EN1 | 5HO4 | 5WWE | 5WWF | 5WWG | 6WPQ | 6WQK | 7WM3 |
Alpha Fold Predicted Structure: AF-P22626-F1


PDB Structures:


1X4B

Structure Description:

Title:
Classification:
Technique:

Abstract of the PDB Structure's related Publication:

Yet to be published

Download RCSB-PDB Structures:

Pdb Files   1X4B.pdb   5EN1.pdb   5HO4.pdb   5WWE.pdb   5WWF.pdb   5WWG.pdb   6WPQ.pdb   6WQK.pdb   7WM3.pdb  
Pdbx/mmCIF Files   1X4B.cif   5EN1.cif   5HO4.cif   5WWE.cif   5WWF.cif   5WWG.cif   6WPQ.cif   6WQK.cif   7WM3.cif  


Protein sequence:

MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY

Comments:





Alpha Fold Predicted Structure:






Clear Selection and Reset Camera

Protein sequence:

M E K T L E T V P L E R K K R E K E Q F R K L F I G G L S F E T T E E S L R N Y Y E Q W G K L T D C V V M R D P A S K R S R G F G F V T F S S M A E V D A A M A A R P H S I D G R V V E P K R A V A R E E S G K P G A H V T V K K L F V G G I K E D T E E H H L R D Y F E E Y G K I D T I E I I T D R Q S G K K R G F G F V T F D D H D P V D K I V L Q K Y H T I N G H N A E V R K A L S R Q E M Q E V Q S S R S G R G G N F G F G D S R G G G G N F G P G P G S N F R G G S D G Y G S G R G F G D G Y N G Y G G G P G G G N F G G S P G Y G G G R G G Y G G G G P G Y G N Q G G G Y G G G Y D N Y G G G N Y G S G N Y N D F G N Y N Q Q P S N Y G P M K S G N F G G S R N M G G P Y G G G N Y G P G G S G G S G G Y G G R S R Y

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-P22626-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-P22626-F1.cif  
DSSP Secondary Structures   P22626.dssp  





Diseases connected to this enzyme:

Description Reaction Disease Name
Expression levels of writers, readers and erasers differs between cancer cell lines; no association of the expression levels of METTL3, YTHDF1, WTAP with overall survival was found; HNRNPA2B1 over-expression is associated with poorer overall survival and promotes endocrine resistance; A:m6A
Breast cancer

Publications:

Title Authors Journal Details PubMed Id DOI