Modomics - A Database of RNA Modifications

ID Card:

Full name: N6-adenosine-methyltransferase non-catalytic subunit MTB
Synonym: Methyltransferase-like protein 1, Protein EMBRYO DEFECTIVE 1691, Protein METTL14 homolog
GI: 75164978
UniProt: Q94AI4
Alpha Fold Predicted Structure: AF-Q94AI4-F1
Complex: MTA



Protein sequence:

MKKKQEESSLEKLSTWYQDGEQDGGDRSEKRRMSLKASDFESSSRSGGSKSKEDNKSVVDVEHQDRDSKRERDGRERTHGSSSDSSKRKRWDEAGGLVNDGDHKSSKLSDSRHDSGGERVSVSNEHGESRRDLKSDRSLKTSSRDEKSKSRGVKDDDRGSPLKKTSGKDGSEVVREVGRSNRSKTPDADYEKEKYSRKDERSRGRDDGWSDRDRDQEGLKDNWKRRHSSSGDKDQKDGDLLYDRGREREFPRQGRERSEGERSHGRLGGRKDGNRGEAVKALSSGGVSNENYDVIEIQTKPHDYVRGESGPNFARMTESGQQPPKKPSNNEEEWAHNQEGRQRSETFGFGSYGEDSRDEAGEASSDYSGAKARNQRGSTPGRTNFVQTPNRGYQTPQGTRGNRPLRGGKGRPAGGRENQQGAIPMPIMGSPFANLGMPPPSPIHSLTPGMSPIPGTSVTPVFMPPFAPTLIWPGARGVDGNMLPVPPVLSPLPPGPSGPRFPSIGTPPNPNMFFTPPGSDRGGPPNFPGSNISGQMGRGMPSDKTSGGWVPPRGGGPPGKAPSRGEQNDYSQNFVDTGMRPQNFIRELELTNVEDYPKLRELIQKKDEIVSNSASAPMYLKGDLHEVELSPELFGTKFDVILVDPPWEEYVHRAPGVSDSMEYWTFEDIINLKIEAIADTPSFLFLWVGDGVGLEQGRQCLKKWGFRRCEDICWVKTNKSNAAPTLRHDSRTVFQRSKEHCLMGIKGTVRRSTDGHIIHANIDTDVIIAEEPPYG

Comments:

Probable non-catalytic subunit of the N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation at the 5'-[AG]GAC-3' consensus sites of some mRNAs. Associates with MTA, FIP37, VIR and HAKAI to form the m6A writer complex which is essential for adenosine methylation at specific mRNA sequences





Alpha Fold Predicted Structure:




Downloading... [139002/683846]


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Protein sequence:

M K K K Q E E S S L E K L S T W Y Q D G E Q D G G D R S E K R R M S L K A S D F E S S S R S G G S K S K E D N K S V V D V E H Q D R D S K R E R D G R E R T H G S S S D S S K R K R W D E A G G L V N D G D H K S S K L S D S R H D S G G E R V S V S N E H G E S R R D L K S D R S L K T S S R D E K S K S R G V K D D D R G S P L K K T S G K D G S E V V R E V G R S N R S K T P D A D Y E K E K Y S R K D E R S R G R D D G W S D R D R D Q E G L K D N W K R R H S S S G D K D Q K D G D L L Y D R G R E R E F P R Q G R E R S E G E R S H G R L G G R K D G N R G E A V K A L S S G G V S N E N Y D V I E I Q T K P H D Y V R G E S G P N F A R M T E S G Q Q P P K K P S N N E E E W A H N Q E G R Q R S E T F G F G S Y G E D S R D E A G E A S S D Y S G A K A R N Q R G S T P G R T N F V Q T P N R G Y Q T P Q G T R G N R P L R G G K G R P A G G R E N Q Q G A I P M P I M G S P F A N L G M P P P S P I H S L T P G M S P I P G T S V T P V F M P P F A P T L I W P G A R G V D G N M L P V P P V L S P L P P G P S G P R F P S I G T P P N P N M F F T P P G S D R G G P P N F P G S N I S G Q M G R G M P S D K T S G G W V P P R G G G P P G K A P S R G E Q N D Y S Q N F V D T G M R P Q N F I R E L E L T N V E D Y P K L R E L I Q K K D E I V S N S A S A P M Y L K G D L H E V E L S P E L F G T K F D V I L V D P P W E E Y V H R A P G V S D S M E Y W T F E D I I N L K I E A I A D T P S F L F L W V G D G V G L E Q G R Q C L K K W G F R R C E D I C W V K T N K S N A A P T L R H D S R T V F Q R S K E H C L M G I K G T V R R S T D G H I I H A N I D T D V I I A E E P P Y G
100200300400500600700SequenceGHTBSN

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-Q94AI4-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-Q94AI4-F1.cif  
DSSP Secondary Structures   Q94AI4.dssp  





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