Modomics - A Database of RNA Modifications

ID Card:

Full name: Ribosomal RNA small subunit methyltransferase, chloroplastic
Synonym: PALEFACE 1, Dimethyladenosine transferase 1C
GI: 75099292
Orf: F22M8.1, T1N6.27
UniProt: O65090
Alpha Fold Predicted Structure: AF-O65090-F1
Complex: none
Enzyme type: methyltransferase



Protein sequence:

MMNAVITSATINCNSLSPSWTCGDNSPSKLLLGEISAALSRRRTVKVSCGKSSPDDYHSTLKSLNSRGRFPRKSLGQHYMLNSDINDQLASAADVKEGDFVLEIGPGTGSLTNVLINLGATVLAIEKDPHMVDLVSERFAGSDKFKVLQEDFVKCHIRSHMLSILETRRLSHPDSALAKVVSNLPFNISTDVVKLLLPMGDIFSKVVLLLQDEAALRLVEPALRTSEYRPINILINFYSEPEYNFRVPRENFFPQPKVDAAVVTFKLKHPRDYPDVSSTKNFFSLVNSAFNGKRKMLRKSLQHISSSPDIEKALGVAGLPATSRPEELTLDDFVKLHNVIARE

Comments:

Required for methylation of the 3' adenosines in the small subunit of plastid rRNA. Essential for chloroplast biogenesis at low temperatures.





Alpha Fold Predicted Structure:






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Protein sequence:

M M N A V I T S A T I N C N S L S P S W T C G D N S P S K L L L G E I S A A L S R R R T V K V S C G K S S P D D Y H S T L K S L N S R G R F P R K S L G Q H Y M L N S D I N D Q L A S A A D V K E G D F V L E I G P G T G S L T N V L I N L G A T V L A I E K D P H M V D L V S E R F A G S D K F K V L Q E D F V K C H I R S H M L S I L E T R R L S H P D S A L A K V V S N L P F N I S T D V V K L L L P M G D I F S K V V L L L Q D E A A L R L V E P A L R T S E Y R P I N I L I N F Y S E P E Y N F R V P R E N F F P Q P K V D A A V V T F K L K H P R D Y P D V S S T K N F F S L V N S A F N G K R K M L R K S L Q H I S S S P D I E K A L G V A G L P A T S R P E E L T L D D F V K L H N V I A R E

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-O65090-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-O65090-F1.cif  
DSSP Secondary Structures   O65090.dssp  





Publications:

Title Authors Journal Details PubMed Id DOI
Chloroplast development at low temperatures requires a homolog of DIM1, a yeast gene encoding the 18S rRNA dimethylase. J G Tokuhisa,P Vijayan,K A Feldmann,J A Browse Plant Cell [details] 9596631 -