ID Card:
Full name:
Decapping and exoribonuclease protein 1
Synonym:
YDR370C
GI:
74583559
UniProt:
Q06349
Alpha Fold Predicted Structure:
AF-Q06349-F1
Enzyme type:
hydrolase
Protein sequence:
MSTEQDAVLGLAKDLEGINLLTVPNLERGHQSKLCKEKTTSDSSSSRKPSQQRDNYRKRRPKLICIPYTSFLHTGMHNFLTKPPRDIFHESKEVALFTNGRAYTILRKDLIPNLKESIAELYESSLLEAKKRKVPYLGHDLFANIDEFVPMTISELDSVSPCFSYIENWILDNPGKDFKIGKKFTVVTTRHHIVDLTMHLFNRRNRQTSLIVTYMGAGLLSFCRNVKKDSQMSKEGIYSNDPNMKKICYSGFEFENWVTENSKVADLTGSKCPIFSLVESKLSEEIGLLIRCEMDAFNPVSETNTELKCFAPLSMHNSNHRRKLLKTWVQTGLLPNSDIMIGLRDSHSGQLLDIQWYSRDLLCKKFNHPGLPTNKKELNYNAQIAVEWCHYCIEAICKLVEANISDYSSTKPESFEIGIDTNNAIVITKLKTTPRNVELFGM
Comments:
Dxo1 is a decapping enzyme that hydrolyzes nicotinamide adenine dinucleotide (NAD) from the 5'-end of a set of NAD-capped RNAs. It acts in a non-canonical way removing the entire cap structure of m7G or incompletely capped RNAs (Chang et al. 2012 ).
Alpha Fold Predicted Structure:
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Protein sequence:
M
S
T
E
Q
D
A
V
L
G
L
A
K
D
L
E
G
I
N
L
L
T
V
P
N
L
E
R
G
H
Q
S
K
L
C
K
E
K
T
T
S
D
S
S
S
S
R
K
P
S
Q
Q
R
D
N
Y
R
K
R
R
P
K
L
I
C
I
P
Y
T
S
F
L
H
T
G
M
H
N
F
L
T
K
P
P
R
D
I
F
H
E
S
K
E
V
A
L
F
T
N
G
R
A
Y
T
I
L
R
K
D
L
I
P
N
L
K
E
S
I
A
E
L
Y
E
S
S
L
L
E
A
K
K
R
K
V
P
Y
L
G
H
D
L
F
A
N
I
D
E
F
V
P
M
T
I
S
E
L
D
S
V
S
P
C
F
S
Y
I
E
N
W
I
L
D
N
P
G
K
D
F
K
I
G
K
K
F
T
V
V
T
T
R
H
H
I
V
D
L
T
M
H
L
F
N
R
R
N
R
Q
T
S
L
I
V
T
Y
M
G
A
G
L
L
S
F
C
R
N
V
K
K
D
S
Q
M
S
K
E
G
I
Y
S
N
D
P
N
M
K
K
I
C
Y
S
G
F
E
F
E
N
W
V
T
E
N
S
K
V
A
D
L
T
G
S
K
C
P
I
F
S
L
V
E
S
K
L
S
E
E
I
G
L
L
I
R
C
E
M
D
A
F
N
P
V
S
E
T
N
T
E
L
K
C
F
A
P
L
S
M
H
N
S
N
H
R
R
K
L
L
K
T
W
V
Q
T
G
L
L
P
N
S
D
I
M
I
G
L
R
D
S
H
S
G
Q
L
L
D
I
Q
W
Y
S
R
D
L
L
C
K
K
F
N
H
P
G
L
P
T
N
K
K
E
L
N
Y
N
A
Q
I
A
V
E
W
C
H
Y
C
I
E
A
I
C
K
L
V
E
A
N
I
S
D
Y
S
S
T
K
P
E
S
F
E
I
G
I
D
T
N
N
A
I
V
I
T
K
L
K
T
T
P
R
N
V
E
L
F
G
M
50 100 150 200 250 300 350 400 Sequence G H T B S N
Secondary Structure Alphabet
G: 3-turn helix (310 helix) H: α-helix I: 𝝅-helix (5 - turn helix) T: Hydrogen Bonded Turn B: β-sheet S: Bend C: Coil (residues not present in any of the above conformations) N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
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