Modomics - A Database of RNA Modifications

ID Card:

Full name: Decapping and exoribonuclease protein
Synonym: DeNADding enzyme DXO
GI: 115311709
UniProt: O77932
Alpha Fold Predicted Structure: AF-O77932-F1
Enzyme type: hydrolase



Protein sequence:

MDPRGTKRGAEKTEVAEPRNKLPRPAPSLPTDPALYSGPFPFYRRPSELGCFSLDAQRQYHGDARALRYYSPPPTNGPGPNFDLRDGYPDRYQPRDEEVQERLDHLLCWLLEHRGRLEGGPGWLAEAIVTWRGHLTKLLTTPYERQEGWQLAASRFQGTLYLSEVETPNARAQRLARPPLLRELMYMGYKFEQYMCADKPGSSPDPSGEVNTNVAFCSVLRSRLGSHPLLFSGEVDCTDPQAPSTQPPTCYVELKTSKEMHSPGQWRSFYRHKLLKWWAQSFLPGVPNVVAGFRNPDGFVSSLKTFPTMKMFEYVRNDRDGWNPSVCMNFCAAFLSFAQSTVVQDDPRLVHLFSWEPGGPVTVSVHQDAPYAFLPIWYVEAMTQDLPSPPKTPSPK

Comments:

Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA





Alpha Fold Predicted Structure:






Clear Selection and Reset Camera

Protein sequence:

M D P R G T K R G A E K T E V A E P R N K L P R P A P S L P T D P A L Y S G P F P F Y R R P S E L G C F S L D A Q R Q Y H G D A R A L R Y Y S P P P T N G P G P N F D L R D G Y P D R Y Q P R D E E V Q E R L D H L L C W L L E H R G R L E G G P G W L A E A I V T W R G H L T K L L T T P Y E R Q E G W Q L A A S R F Q G T L Y L S E V E T P N A R A Q R L A R P P L L R E L M Y M G Y K F E Q Y M C A D K P G S S P D P S G E V N T N V A F C S V L R S R L G S H P L L F S G E V D C T D P Q A P S T Q P P T C Y V E L K T S K E M H S P G Q W R S F Y R H K L L K W W A Q S F L P G V P N V V A G F R N P D G F V S S L K T F P T M K M F E Y V R N D R D G W N P S V C M N F C A A F L S F A Q S T V V Q D D P R L V H L F S W E P G G P V T V S V H Q D A P Y A F L P I W Y V E A M T Q D L P S P P K T P S P K
50100150200250300350SequenceGHITBSN

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-O77932-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-O77932-F1.cif  
DSSP Secondary Structures   O77932.dssp  





Publications: