ID Card:
PDB Structures:
1VK6
2GB5
5ISY
5IW4
5IW5
7E44
}
1VK6
Structure Description:
Title:
Crystal structure of NADH pyrophosphatase (1790429) from Escherichia coli k12 at 2.20 A resolution
Classification:
HYDROLASE
X-Ray Diffraction
2.2
0.22
0.188
0.187
Abstract of the PDB Structure's related Publication:
Download RCSB-PDB Structures:
Protein sequence:
MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE
Comments:
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. Has preference for mRNAs with a 5'-end purine.
Alpha Fold Predicted Structure:
Parsing response... [246260/246260]
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Protein sequence:
M
D
R
I
I
E
K
L
D
H
G
W
W
V
V
S
H
E
Q
K
L
W
L
P
K
G
E
L
P
Y
G
E
A
A
N
F
D
L
V
G
Q
R
A
L
Q
I
G
E
W
Q
G
E
P
V
W
L
V
Q
Q
Q
R
R
H
D
M
G
S
V
R
Q
V
I
D
L
D
V
G
L
F
Q
L
A
G
R
G
V
Q
L
A
E
F
Y
R
S
H
K
Y
C
G
Y
C
G
H
E
M
Y
P
S
K
T
E
W
A
M
L
C
S
H
C
R
E
R
Y
Y
P
Q
I
A
P
C
I
I
V
A
I
R
R
D
D
S
I
L
L
A
Q
H
T
R
H
R
N
G
V
H
T
V
L
A
G
F
V
E
V
G
E
T
L
E
Q
A
V
A
R
E
V
M
E
E
S
G
I
K
V
K
N
L
R
Y
V
T
S
Q
P
W
P
F
P
Q
S
L
M
T
A
F
M
A
E
Y
D
S
G
D
I
V
I
D
P
K
E
L
L
E
A
N
W
Y
R
Y
D
D
L
P
L
L
P
P
P
G
T
V
A
R
R
L
I
E
D
T
V
A
M
C
R
A
E
Y
E
20 40 60 80 100 120 140 160 180 200 220 240 Sequence G H T B S N
Secondary Structure Alphabet
G: 3-turn helix (310 helix) H: α-helix I: 𝝅-helix (5 - turn helix) T: Hydrogen Bonded Turn B: β-sheet S: Bend C: Coil (residues not present in any of the above conformations) N: Not assigned
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