Modomics - A Database of RNA Modifications

ID Card:

Full name: Pseudouridylate synthase PUS7L
Synonym: Pseudouridylate synthase 7 homolog-like protein
UniProt: Q9H0K6
Alpha Fold Predicted Structure: AF-Q9H0K6-F1
Enzyme type: isomerase



Protein sequence:

MEEDTDYRIRFSSLCFFNDHVGFHGTIKSSPSDFIVIEIDEQGQLVNKTIDEPIFKISEIQLEPNNFPKKPKLDLQNLSLEDGRNQEVHTLIKYTDGDQNHQSGSEKEDTIVDGTSKCEEKADVLSSFLDEKTHELLNNFACDVREKWLSKTELIGLPPEFSIGRILDKNQRASLHSAIRQKFPFLVTVGKNSEIVVKPNLEYKELCHLVSEEEAFDFFKYLDAKKENSKFTFKPDTNKDHRKAVHHFVNKKFGNLVETKSFSKMNCSAGNPNVVVTVRFREKAHKRGKRPLSECQEGKVIYTAFTLRKENLEMFEAIGFLAIKLGVIPSDFSYAGLKDKKAITYQAMVVRKVTPERLKNIEKEIEKKRMNVFNIRSVDDSLRLGQLKGNHFDIVIRNLKKQINDSANLRERIMEAIENVKKKGFVNYYGPQRFGKGRKVHTDQIGLALLKNEMMKAIKLFLTPEDLDDPVNRAKKYFLQTEDAKGTLSLMPEFKVRERALLEALHRFGMTEEGCIQAWFSLPHSMRIFYVHAYTSKIWNEAVSYRLETYGARVVQGDLVCLDEDIDDENFPNSKIHLVTEEEGSANMYAIHQVVLPVLGYNIQYPKNKVGQWYHDILSRDGLQTCRFKVPTLKLNIPGCYRQILKHPCNLSYQLMEDHDIDVKTKGSHIDETALSLLISFDLDASCYATVCLKEIMKHDV

Comments:





Alpha Fold Predicted Structure:






Clear Selection and Reset Camera

Protein sequence:

M E E D T D Y R I R F S S L C F F N D H V G F H G T I K S S P S D F I V I E I D E Q G Q L V N K T I D E P I F K I S E I Q L E P N N F P K K P K L D L Q N L S L E D G R N Q E V H T L I K Y T D G D Q N H Q S G S E K E D T I V D G T S K C E E K A D V L S S F L D E K T H E L L N N F A C D V R E K W L S K T E L I G L P P E F S I G R I L D K N Q R A S L H S A I R Q K F P F L V T V G K N S E I V V K P N L E Y K E L C H L V S E E E A F D F F K Y L D A K K E N S K F T F K P D T N K D H R K A V H H F V N K K F G N L V E T K S F S K M N C S A G N P N V V V T V R F R E K A H K R G K R P L S E C Q E G K V I Y T A F T L R K E N L E M F E A I G F L A I K L G V I P S D F S Y A G L K D K K A I T Y Q A M V V R K V T P E R L K N I E K E I E K K R M N V F N I R S V D D S L R L G Q L K G N H F D I V I R N L K K Q I N D S A N L R E R I M E A I E N V K K K G F V N Y Y G P Q R F G K G R K V H T D Q I G L A L L K N E M M K A I K L F L T P E D L D D P V N R A K K Y F L Q T E D A K G T L S L M P E F K V R E R A L L E A L H R F G M T E E G C I Q A W F S L P H S M R I F Y V H A Y T S K I W N E A V S Y R L E T Y G A R V V Q G D L V C L D E D I D D E N F P N S K I H L V T E E E G S A N M Y A I H Q V V L P V L G Y N I Q Y P K N K V G Q W Y H D I L S R D G L Q T C R F K V P T L K L N I P G C Y R Q I L K H P C N L S Y Q L M E D H D I D V K T K G S H I D E T A L S L L I S F D L D A S C Y A T V C L K E I M K H D V

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-Q9H0K6-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-Q9H0K6-F1.cif  
DSSP Secondary Structures   Q9H0K6.dssp  





Publications:

Title Authors Journal Details PubMed Id DOI
Eukaryotic stand-alone pseudouridine synthases – RNA modifying enzymes and emerging regulators of gene expression? Anne C. Rintala-Dempsey and Ute Kothe [details] 28045575 10.1080/15476286.2016.1276150