Modomics - A Database of RNA Modifications

ID Card:

Full name: 23S rRNA (guanosine(2553)-2'-O)-methyltransferase RlmP
Synonym: ysgA
UniProt: P94538
Alpha Fold Predicted Structure: AF-P94538-F1
Enzyme type: methylthiotransferase



Protein sequence:

MKQIESAKNQKVKDWKKLHTKKERTKTNTFLIEGEHLVEEALKSPGIVKEILVKDETRIPSDLETGIQCYMLSEDAFSAVTETETPQQIAAVCHMPEEKLATARKVLLIDAVQDPGNLGTMIRTADAAGLDAVVLGDGTADAFNGKTLRSAQGSHFHIPVVRRNLPSYVDELKAEGVKVYGTALQNGAPYQEIPQSESFALIVGNEGAGVDAALLEKTDLNLYVPLYGQAESLNVAVAAAILVYHLRG

Comments:

The Bacillus subtilis open reading frame ysgA encodes the SPOUT methyltransferase RlmP forming 2'-O-methylguanosine at position 2553 in the A-loop of 23S rRNA





Alpha Fold Predicted Structure:






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Protein sequence:

M K Q I E S A K N Q K V K D W K K L H T K K E R T K T N T F L I E G E H L V E E A L K S P G I V K E I L V K D E T R I P S D L E T G I Q C Y M L S E D A F S A V T E T E T P Q Q I A A V C H M P E E K L A T A R K V L L I D A V Q D P G N L G T M I R T A D A A G L D A V V L G D G T A D A F N G K T L R S A Q G S H F H I P V V R R N L P S Y V D E L K A E G V K V Y G T A L Q N G A P Y Q E I P Q S E S F A L I V G N E G A G V D A A L L E K T D L N L Y V P L Y G Q A E S L N V A V A A A I L V Y H L R G
20406080100120140160180200220240SequenceGHTBSN

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-P94538-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-P94538-F1.cif  
DSSP Secondary Structures   P94538.dssp  





Publications: