ID Card:
Full name:
18S rRNA aminocarboxypropyltransferase
UniProt:
Q9UJK0
Alpha Fold Predicted Structure:
AF-Q9UJK0-F1
Enzyme type:
methyltransferase
Protein sequence:
MGRRRAARGPGAEGGRPRHLPTRSLEAFAEEVGAALQASVEPGAADGEGGPGPAALPCTLAMWELGHCDPRRCTGRKLARLGLVRCLRLGHRFGGLVLSPVGKQYASPADRQLVAQSGVAVIDCSWARLDETPFGKMRGSHLRLLPYLVAANPVNYGRPYRLSCVEAFAATFCIVGFPDLAVILLRKFKWGKGFLDLNRQLLDKYAACGSPEEVLQAEQEFLANAKESPQEEEIDPFDVDSGREFGNPNRPVASTRLPSDTDDSDASEDPGPGAERGGASSSCCEEEQTQGRGAEARAPAEVWKGIKKRQRD
Comments:
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA (Probable). It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxy propyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA (Meyer et a. 2016 )
Alpha Fold Predicted Structure:
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Protein sequence:
M
G
R
R
R
A
A
R
G
P
G
A
E
G
G
R
P
R
H
L
P
T
R
S
L
E
A
F
A
E
E
V
G
A
A
L
Q
A
S
V
E
P
G
A
A
D
G
E
G
G
P
G
P
A
A
L
P
C
T
L
A
M
W
E
L
G
H
C
D
P
R
R
C
T
G
R
K
L
A
R
L
G
L
V
R
C
L
R
L
G
H
R
F
G
G
L
V
L
S
P
V
G
K
Q
Y
A
S
P
A
D
R
Q
L
V
A
Q
S
G
V
A
V
I
D
C
S
W
A
R
L
D
E
T
P
F
G
K
M
R
G
S
H
L
R
L
L
P
Y
L
V
A
A
N
P
V
N
Y
G
R
P
Y
R
L
S
C
V
E
A
F
A
A
T
F
C
I
V
G
F
P
D
L
A
V
I
L
L
R
K
F
K
W
G
K
G
F
L
D
L
N
R
Q
L
L
D
K
Y
A
A
C
G
S
P
E
E
V
L
Q
A
E
Q
E
F
L
A
N
A
K
E
S
P
Q
E
E
E
I
D
P
F
D
V
D
S
G
R
E
F
G
N
P
N
R
P
V
A
S
T
R
L
P
S
D
T
D
D
S
D
A
S
E
D
P
G
P
G
A
E
R
G
G
A
S
S
S
C
C
E
E
E
Q
T
Q
G
R
G
A
E
A
R
A
P
A
E
V
W
K
G
I
K
K
R
Q
R
D
50 100 150 200 250 300 Sequence G H T B S N
Secondary Structure Alphabet
G: 3-turn helix (310 helix) H: α-helix I: 𝝅-helix (5 - turn helix) T: Hydrogen Bonded Turn B: β-sheet S: Bend C: Coil (residues not present in any of the above conformations) N: Not assigned
Download PDB Structures & DSSP Secondary Structures:
Publications: