Modomics - A Database of RNA Modifications

ID Card:

Full name: Multifunctional methyltransferase subunit TRM112-like protein
UniProt: Q9VP65
Alpha Fold Predicted Structure: AF-Q9VP65-F1



Protein sequence:

MKLSTYNFLTSVAIKGVKVGFPLKLTINKKEVVESEFNPTFVERILPKLDWSAVYGAAQVAELTEDIPAVQPENIVENELLLQKLHHLLFEIDVLEGQLECPETGRVFPISDGIPNMLLNEDEV

Comments:

Acts as an activator of both RNA and protein methyltransferases .





Alpha Fold Predicted Structure:






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Protein sequence:

M K L S T Y N F L T S V A I K G V K V G F P L K L T I N K K E V V E S E F N P T F V E R I L P K L D W S A V Y G A A Q V A E L T E D I P A V Q P E N I V E N E L L L Q K L H H L L F E I D V L E G Q L E C P E T G R V F P I S D G I P N M L L N E D E V

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-Q9VP65-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-Q9VP65-F1.cif  
DSSP Secondary Structures   Q9VP65.dssp  





Publications:

Title Authors Journal Details PubMed Id DOI
The 18S ribosomal RNA m6 A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. Jessica Leismann # 1, Mariangela Spagnuolo # 1, Mihika Pradhan 1, Ludivine Wacheul 2, Minh Anh Vu 1, Michael Musheev 1, Pablo Mier 3, Miguel A Andrade-Navarro 3, Marc Graille 4, Christof Niehrs 1 5, Denis Lj Lafontaine 2, Jean-Yves Roignant 1 [details] 32350990 10.15252/embr.201949443