| Full name: | RNA-directed RNA polymerase NS5 |
|---|---|
| UniProt: | Q5WPU5 |
| Enzyme type: | methyltransferase |
GRPGGRTLGEQWKEKLNGLSKEDFLKYRKEAITEVDRSAARKARRDGNKTGGHPVSRGSAKLRWMVERQFVKPIGKVVDLGCGRGGWSYYAATLKGVQEVRGYTKGGPGHEEPMLMQSYGWNLVTMKSGVDVYYKPSEPCDTLFCDIGESSSSAEVEEQRTLRILEMVSDWLQRGPREFCIKVLCPYMPRVMERLEVLQRRYGGGLVRVPLSRNSNHEMYWVSGAAGNIVHAVNMTSQVLIGRMEKRTWHGPKYEEDVNLGSGTRAVGKPQPHTNQEKIKARIQRLKEEYAATWHHDKDHPYRTWTYHGSYEVKPTGSASSLVNGVVRLMSKPWDAILNVTTMAMTDTTPFGQQRVFKEKVDTKAPEPPSGVREVMDETTNWLWAFLAREKKPRLCTREEFKRKVNSNAALGAMFEEQNQWSSAREAVEDPRFWEMVDEERENHLKGECHTCIYNMMGKREKKLGEFGKAKGSRAIWFMWLGARFLEFEALGFLNEDHWLGRKNSGGGVEGLGVQKLGYILREMSHHSGGKMYADDTAGWDTRITRADLDNEAKVLELMEGEHRQLARAIIELTYKHKVVKVMRPGTDGKTVMDVISREDQRGSGQVVTYALNTFTNIAVQLIRLMEAEGVIGQEHLESLPRKTKYAVRTWLFENGEERVTRMAVSGDDCVVKPLDDRFANALHFLNSMSKVRKDVPEWKPSSGWHDWQQVPFCSNHFQELIMKDGRTLVVPCRGQDELIGRARVSPGSGWNVRDTACLAKAYAQMWLLLYFHRRDLRLMANAICSAVPSNWVPTGRTSWSVHATGEWMTTDDMLEVWNKVWIQDNEWMLDKTPVQSWTDIPYTGKREDIWCGSLIGTRTRATWAENIYAAINQVRAIIGQEKYRDYMLSLRRYEEVNVQEDRVL
Replicates the viral, and performs the capping of genomes in the cytoplasm. NS5 methylates viral RNA cap at guanine N-7 and ribose 2'-O positions.