ID Card:
| Full name: |
Ribosomal RNA large subunit methyltransferase Q |
| Enzyme type: |
|
| Position of modification - modification: |
:2601(None) - m7G
|
| Level of experimental evidence: |
3 |
| Level of experimental reliability: |
2 |
Protein sequence:
Comments:
RlmQ is responsible in vivo for the methylation at position 7 of G2601 located in helix H90 of the 23S rRNA. Importantly, this position is unmodified in E. coli (G2574) hinting at a specific function in S. aureus.
| Reaction |
Substrate |
SubstrateType |
Position |
(Anti)Codon |
Modified (Anti)Codon |
Amino Acid Change |
Transcript Name |
Transcript Region |
Cellular Localization |
References |
|
G:m7G
|
rRNA (r) |
rRNA/rRNA/prokaryotic cytosol |
2601 |
|
|
|
|
|
|
|
Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| RlmQ: a newly discovered rRNA modification enzyme bridging RNA modification and virulence traits in <i>Staphylococcus aureus</i>. |
Bahena-Ceron R; Teixeira C; Ponce JRJ; Wolff P; Couzon F; François P; Klaholz BP; Vandenesch F; Romby P; Moreau K; Marzi S |
RNA |
[details]
|
38164596
|
10.1261/rna.079850.123
|