ID Card:
| Full name: |
U6 small nuclear RNA (adenine-(64)-N(6))-methyltransferase |
| Complex: |
Pof8, Thc1, snoZ30, sno530 |
| Enzyme type: |
|
| Position of modification - modification: |
n:64 - m6A
|
| Level of experimental evidence: |
3 |
| Level of experimental reliability: |
2 |
Protein sequence:
Comments:
Bmc1 and Pof8 are required for the formation of a distinct U6 snRNP that promotes 2′-O-methylation of U6,
| Reaction |
Substrate |
SubstrateType |
Position |
(Anti)Codon |
Modified (Anti)Codon |
Amino Acid Change |
Transcript Name |
Transcript Region |
Cellular Localization |
References |
|
A:m6A
|
snRNA (sn) |
snRNA/snRNA/eukaryotic nucleoplasm |
64 |
|
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Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| The fission yeast methyl phosphate capping enzyme Bmc1 guides 2'-O-methylation of the U6 snRNA. |
Porat J; Slat VA; Rader SD; Bayfield MA |
Nucleic Acids Res |
[details]
|
37403782
|
10.1093/nar/gkad563
|