ID Card:
| Full name: |
tRNA (guanine(26)-N(2))-dimethyltransferase |
| Synonym: |
HVO_0236 |
| UniProt: |
D4GZI1 |
| Enzyme type: |
|
| Position of modification - modification: |
t:None - m2G
|
| Level of experimental evidence: |
5 |
| Level of experimental reliability: |
5 |
Protein sequence:
MHVSEGGVEIEVPDARDGASAGTGDDVFYNPTQELNRDITAAVLRAFREREPRAESYLDAMAASGIRGVRAAAEGYDVTCADLDADAVELAQSNLDRAGNGGEAVHRNANALMYDEVFDVVDLDPFGTPMPFADPTFANTRDLVCVTATDTAPLCGAHQKSGIRKYGCLPQNTDYHPEMGLRTLLGAMVRTAARYDKAAVPILSHATRHYARAYLELDERATKADELLESTGFVYHCEDCLHREAERSLVAHPPEACANCDSTRILEAGPIWLGPVSEPAFAGAVRDEVTEDFGTAKRARKLLDTLAVELDTPTHFDQHRLCKLWGRSASKMETFLETLRDAGYDATPAHYHGTAFKTDATVAEIREVTAALDPEA
Comments:
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
| Reaction |
Substrate |
SubstrateType |
Position |
(Anti)Codon |
Modified (Anti)Codon |
Amino Acid Change |
Transcript Name |
Transcript Region |
Cellular Localization |
References |
|
G:m2G
|
tRNA (t) |
tRNA/tRNA/prokaryotic cytosol |
26 |
|
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|
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|
Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes. |
Grosjean H; Gaspin C; Marck C; Decatur WA; de Crécy-Lagard V |
BMC Genomics |
[details]
|
18844986
|
10.1186/1471-2164-9-470
|