| Full name: | tRNA-uridine aminocarboxypropyltransferase |
|---|---|
| UniProt: | Q47319 |
| Enzyme type: | |
| Position of modification - modification: |
t:None - acp3U |
| Level of experimental evidence: | 2 |
| Level of experimental reliability: | 2 |
MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCSTITPAQAKSRFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSQDLLELVQNPDYQPMVVFPASYADEQREVIFTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDNLPVISVDLSRLSAYRLREAQAEGQYCTAEVAIALLDMAGDTGAAAGLGEHFTRFKTRYLAGKTQHLGSITAEQLESV
Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 47 of tRNAs
| Reaction | Substrate | SubstrateType | Position | (Anti)Codon | Modified (Anti)Codon | Amino Acid Change | Transcript Name | Transcript Region | Cellular Localization | References |
|---|---|---|---|---|---|---|---|---|---|---|
| U:acp3U | tRNA (t) | tRNA/tRNA/prokaryotic cytosol | 47 |
| Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|
| Biogenesis and functions of aminocarboxypropyluridine in tRNA. | Takakura M; Ishiguro K; Akichika S; Miyauchi K; Suzuki T | Nat Commun | [details] | 31804502 | 10.1038/s41467-019-13525-3 |
| Identification of the 3-amino-3-carboxypropyl (acp) transferase enzyme responsible for acp3U formation at position 47 in Escherichia coli tRNAs. | Meyer B; Immer C; Kaiser S; Sharma S; Yang J; Watzinger P; Weiß L; Kotter A; Helm M; Seitz HM; Kötter P; Kellner S; Entian KD; Wöhnert J | Nucleic Acids Res | [details] | 31863583 | 10.1093/nar/gkz1191 |
| Enzymatic synthesis of 3-(3-amino-3-carboxypropyl)uridine in Escherichia coli phenylalanine transfer RNA: transfer of the 3-amino-acid-3-carboxypropyl group from S-adenosylmethionine. | Nishimura S; Taya Y; Kuchino Y; Oashi Z | Biochem Biophys Res Commun | [details] | 4597321 | - |