Modomics - A Database of RNA Modifications

ID Card:

Full name:	tRNA pseudouridine synthase 3
Synonym:	Deg1p, Hrm3
GI:	399356
Orf:	YFL001W
COG:	COG0101
UniProt:	P31115
Structures:	\| \|
Enzyme type:	pseudouridine synthase
Position of modification - modification:	t:39 - Y t:38 - Y

Protein sequence:

MSNFIRRLVGKMKAISTGTNAIVSKKDSIYANWSKEQLIRRITELENANKPHSEKFQHIEDNKKRKISQEEVTRSKAKKAPKKFDFSKHNTRFIALRFAYLGWNYNGLAVQKEYTPLPTVEGTILEAMNKCKLVPSMVLQDYKFSRCGRTDKGVSAMNQVISLEVRSNLTDEEQRDPTNDSREIPYVHVLNQLLPDDIRISAVCLRPPPNFDARFSCVHRHYKYIFNGKNLNIEKMSKAASYFVGERDFRNFCKLDGSKQITNFKRTIISSKILPLSETFYCFDLVGSAFLWHQVRCMMAILFLVGQSLEVPEIVLRLTDIEKTPQRPVYEMANDIPLLLYDCKFPEMDWQEPTVDDYKAIKFTTATEALTLHYELKAAVCNIFKDVLPTANTNNFSKTIINLGDGRGKVVGTYVKLEDRSVMEPVEVVNAKYSKKKNNKNK

Comments:

Region specificity.Monomeric enzyme.

Search:

Reaction	Substrate	SubstrateType	Position
U:Y	tRNA (t)	Ala/IGC/prokaryotic cytosol	38
U:Y	tRNA (t)	Gly/GCC/prokaryotic cytosol	38
U:Y	tRNA (t)	Arg/ACU/prokaryotic cytosol	39
U:Y	tRNA (t)	Asn/GUU/prokaryotic cytosol	39
U:Y	tRNA (t)	Cys/GCA/prokaryotic cytosol	39
U:Y	tRNA (t)	His/GUG/prokaryotic cytosol	39
U:Y	tRNA (t)		39
U:Y	tRNA (t)	Leu/CAA/prokaryotic cytosol	39
U:Y	tRNA (t)		39
U:Y	tRNA (t)	Lys/CUU/prokaryotic cytosol	39
U:Y	tRNA (t)	Met/CAU/prokaryotic cytosol	39
U:Y	tRNA (t)	Phe/GAA/prokaryotic cytosol	39
U:Y	tRNA (t)	Ser/CGA/prokaryotic cytosol	39
U:Y	tRNA (t)	Ser/UGA/prokaryotic cytosol	39
U:Y	tRNA (t)	Ser/IGA/prokaryotic cytosol	39
U:Y	tRNA (t)	Thr/IGU/prokaryotic cytosol	39
U:Y	tRNA (t)	Trp/CCA/prokaryotic cytosol	39
U:Y	tRNA (t)	Tyr/GUA/prokaryotic cytosol	39
U:Y	tRNA (t)	His/GUG/mitochondrion	38
U:Y	tRNA (t)	Thr/UAG/mitochondrion	38
U:Y	tRNA (t)	Arg/UCU/mitochondrion	39
U:Y	tRNA (t)	Arg/ACG/mitochondrion	39
U:Y	tRNA (t)	Leu/UAA/mitochondrion	39
U:Y	tRNA (t)	Phe/GAA/mitochondrion	39
U:Y	tRNA (t)	Ser/UGA/mitochondrion	39
U:Y	tRNA (t)	Trp/UCA/mitochondrion	39


U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y
U:Y

Showing 1 to 26 of 26 entries

Publications:

Search:

Title	Authors	Journal	Details	PubMed Id	DOI
Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop.	Lecointe F, Simos G, Sauer A, Hurt EC, Motorin Y, Grosjean H	J Biol Chem	[details]	9430663	-


Characterization of yeast protein Deg1 as pseudouridine synthase (Pus3) catalyzing the formation of psi 38 and psi 39 in tRNA anticodon loop.

Showing 1 to 1 of 1 entries