Modomics - A Database of RNA Modifications

ID Card:

Full name: tRNA pseudouridine synthase 9, mitochondrial
GI: 6320168
Orf: YDL036c
COG: COG0564
UniProt: Q12069
Structures: | |
Enzyme type: pseudouridine synthase
Position of modification - modification: t:32 - Y



Protein sequence:

MQRNNRLRNLFTVPVIMARQLKRNALSAGLAFAGNATSNEFDEHLQNEVEREREIQKKKKIKRTQSKKSPDLINKSTFQSRTIGSKKEKHRQLDPEYEIVIDGPLRKIKPYHFTYRTFCKERWRDKKLVDVFISEFRDRESEYYKRTIENGDVHINDETADLSTVIRNGDLITHQVHRHEPPVTSRPIKVIFEDDNIMVIDKPSGIPVHPTGRYRFNTITKMLQNNLGFVVNPCNRLDRLTSGLMFLAKTPKGADNIGDQLKAREVTKEYVAKVVGEFPETEVIVEKPLKLIEPRLALNAVCQMDEKGAKHAKTVFNRISYDGKTSIVKCKPLTGRSHQIRVHLQYLGHPIANDPIYSNDEVWGNNLGKGGQADFDIVITKLDEIGKRKPAKSWFHSNGGYGEVLRQEKCSICESDLYTDPGPNDLDLWLHAYLYESTETEEGTEKKKWCYKTEYPEWALRR

Comments:

Mitochondrial enzyme. In the absence of Pus8 works also in cytoplasm.




Reaction Substrate SubstrateType Position (Anti)Codon Modified (Anti)Codon Amino Acid Change Transcript Name Transcript Region Cellular Localization References
U:Y tRNA (t) His/GUG/mitochondrion 32
U:Y tRNA (t) Phe/GAA/mitochondrion 32
U:Y tRNA (t) Pro/UGG/mitochondrion 32
U:Y tRNA (t) Ser/UGA/mitochondrion 32
U:Y tRNA (t) Ser/GCU/mitochondrion 32
U:Y tRNA (t) Trp/UCA/mitochondrion 32



Publications:

Title Authors Journal Details PubMed Id DOI
Pseudouridylation at position 32 of mitochondrial and cytoplasmic tRNAs requires two distinct enzymes in Saccharomyces cerevisiae. Behm-Ansmant I, Grosjean H, Massenet S, Motorin Y, Branlant C J Biol Chem [details] 15466869 -