Published on Nov. 1, 2006 in Nucleic Acids Symposium volume Ser (November 2006) 50 (1).

DOI: 10.1093/nass/nrl005

Abstract:

Recently, a novel base-modified uridine derivative, 5-taurinomethyluridine (τm5U) was discovered from bovine and human mitochondrial tRNAs, and this modified ribonucleoside was found to existed at the first position of the anti-codon. We report efficient reactions for the synthesis of RNA oligomers including this base-modified ribonucleotide.