Modomics - A Database of RNA Modifications

IUPAC Name 2‑(trimethylsilyl)ethyl
Protecting group 1-hydroxy function of threonyl
Deprotection fluoride labile group
Synthesis reagent 2‑(trimethylsilyl)ethyl hydroxide

Protection group:

Can be found in the following building blocks:

N6-threonylcarbamoyladenosine (BB2) 24719-82-2

Publications

Title Authors Journal Details PubMed Id DOI
Synthesis and Characterization of the Native Anticodon Domain of E. coli tRNALys:  Simultaneous Incorporation of Modified Nucleosides mnm5s2U, t6A, and Pseudouridine Using Phosphoramidite Chemistry Mallikarjun Sundaram, Pamela F. Crain, and Darrell R. Davis J. Org. Chem. [details] 10970299 10.1021/jo000338b
Synthesis of the tRNALys,3 Anticodon Stem-Loop Domain Containing the Hypermodified ms2t6A Nucleoside Bajji AC, Davis DR. J. Org. Chem [details] 12126427 10.1021/jo025826t
Introduction of hypermodified nucleotides in RNA. Davis DR, Bajji AC Methods Mol Biol [details] 15333904 -