Modomics - A Database of RNA Modifications

IUPAC Name bis (2‑acetoxyethoxy)methyl
Protecting group 2'-ribose
Deprotection fluoride labile group
Synthesis reagent tris(2-acetoxyethoxy)orthoformate

Protection group:

Can be found in the following building blocks:

3-methylpseudouridine 81691-06-7
3-methyluridine (BB2) 2140-69-4
pseudouridine 1445-07-4


Title Authors Journal Details PubMed Id DOI
Unique structural and stabilizing roles for the individual pseudouridine residues in the 1920 region of Escherichia coli 23S rRNA. Meroueh M, Grohar PJ, Qiu J, SantaLucia J Jr, Scaringe SA, Chow CS Nucleic Acids Res [details] 10773075 -
Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin. Chui HM, Meroueh M, Scaringe SA, Chow CS Bioorg Med Chem [details] 11741781 -
Synthesis of helix 69 of Escherichia coli 23S rRNA containing its natural modified nucleosides, m(3)Psi and Psi. Chui HM, Desaulniers JP, Scaringe SA, Chow CS J Org Chem [details] 12467398 -

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