Modomics - A Database of RNA Modifications

IUPAC Name chloroacetyl
Protecting group N6-adenine
Deprotection ammonia in methanol
Synthesis reagent chloroacetic anhydride

Protection group:

Can be found in the following building blocks:

1-methyladenosine 15763-06-1
1-methyladenosine (BB2) 15763-06-1
N6-isopentenyladenosine 7724-76-7

Publications

Title Authors Journal Details PubMed Id DOI
Chemical incorporation of 1‑methyladenosine into oligonucleotides Mikhailov SN, Rozenski J, Efimtseva EV et al. Nucl. Acids Res. [details] 11861902 10.1093/nar/30.5.1124
Synthesis of 2′-O-[(Triisopropylsilyl)oxy]methyl (= tom)-Protected Ribonucleoside Phosphoramidites Containing Various Nucleobase Analogues Porcher S, Pitsch S. HELVETICA CHIMICA ACTA [details] - 10.1002/hlca.200590209