Modomics - A Database of RNA Modifications

IUPAC Name trifluoracetyl
Protecting group base protection
Deprotection base labile
Synthesis reagent trifluoracetyl chloride

Protection group:

Can be found in the following building blocks:

5-methylaminomethyl-2-thiouridine 32860-54-1
5-methylaminomethyluridine 72667-55-1

Publications

Title Authors Journal Details PubMed Id DOI
Site-selected introduction of modified purine and pyrimidine ribonucleosides into RNA by automated phosphoramidite chemistry. Agris PF, Malkiewicz A, Kraszewski A et al. Biochimie [details] 7599270 10.1016/0300-9084(96)88115-6
Synthesis and Characterization of the Native Anticodon Domain of E. coli tRNALys:  Simultaneous Incorporation of Modified Nucleosides mnm5s2U, t6A, and Pseudouridine Using Phosphoramidite Chemistry Mallikarjun Sundaram, Pamela F. Crain, and Darrell R. Davis J. Org. Chem. [details] 10970299 10.1021/jo000338b
Introduction of hypermodified nucleotides in RNA. Davis DR, Bajji AC Methods Mol Biol [details] 15333904 -

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