General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000676467
Gene ID:	ENSG00000143801
Gene Name:	PSEN2
Sequence (UNICHARACTER ENCODING)	CGGUCCCUUCCCCGGCUGUGGGUCUGCGGCCCCUGCGUGCGCAGCGCUCCUGGCCUCUGCGGCCAGCGCGGGGGCGGAGAGAGGAGAGUGCCCGGCAGGCGGCGGCUGGGCCGGCCCGGAACUGGGUCGUGGAAGGAUCGCGGGGAGCGGCCCUCAGGCCUUCGGCCUCACUGCGUCCCCACUUCCCUGCGCCCGCCUGCCGCCGAGCCCCGGCUGGGGGUGGGCGCGGCGCGAGCGGUUAAAGGGCCGGUGCAUUUAAAGGAGCGGUGCACGUGGGUCUCUGAGGCGUGUAGCAGGCGGGGGCGUUUUGUUCUUCUUCUCUCUCGCCGGAGACCUCCGUUGCGCCGAGUCCAUUCGGCCUCUAGCACCGGGUCCUGGGCAUGCUUUCCCCGGGAAGGAGGCGCGCGGGGGCUCUGCCCGCACGUGAGGGGCAGGGCCGCAGGCUCAAGCCUAGAGCCGGUUUCUGUUAGCAGCGGUGUUUGGCUGUUUUAUCAGGCAUUUCCAGCAGUGAGGAGACAGCCAGAAGCAAGCUUUUGGAGCUGAAGGAACCUGAGACAGAAGCUAGUCCCCCCUCUGAAUUUUACUGAUGAAGAAACUGAGGCCACAGAGCUAAAGUGACUUUUCCCAAGGUCGCCCAGCGAGGACGUGGGACUUCUCAGACGUCAGGAGAGUGAUGUGAGGGAGCUGUGUGACCAUAGAAAGUGACGUGUUAAAAACCAGCGCUGCCCUCUUUGAAAGCCAGGGAGCAUCAUUCAUUUAGCCUGCUGAGAAGAAGAAACCAAGUGUCCGGGAUUCAGACCUCUCUGCGGCCCCAAGUGUUCGUGGUGCUUCCAGAGGCAGGGCUAUGCUCACAUUCAUGGCCUCUGACAGCGAGGAAGAAGUGUGUGAUGAGCGGACGUCCCUAAUGUCGGCUGAGAGCCCCACGCCGCGCUCCUGCCAGGAGGGCAGGCAGGGCCCAGAGGAUGGAGAGAACACUGCCCAGUGGCCAGGAGAACGAGGAGGACGGUGAGGAGGACCCUGACCGCUAUGUCUGUAGUGGGGUUCCCGGGCGGCCGCCAGGCCUGGAGGAAGAGCUGACCCUCAAAUACGGAGCGAAGCACGUGAUCAUGCUGUUUGUGCCUGUCACUCUGUGCAUGAUCGUGGUGGUAGCCACCAUCAAGUCUGUGCGCUUCUACACAGAGAAGAAUGGACAGCUCAUCUACACGCCAUUCACUGAGGACACACCCUCGGUGGGCCAGCGCCUCCUCAACUCCGUGCUGAACACCCUCAUCAUGAUCAGCGUCAUCGUGGUUAUGACCAUCUUCUUGGUGGUGCUCUACAAGUACCGCUGCUACAAGUUCAPCCAUGGCUGGUUGAUCAUGUCUUCACUGAUGCUGCUGUUCCUCUUCACCUAUAUCUACCUUGGGGAAGUGCUCAAGACCUACAAUGUGGCCAUGGACUACCCCACCCUCUUGCUGACUGUCUGGAACUUCGGGGCAGUGGGCAUGGUGUGCAPCCACUGGAAGGGCCCUCUGGUGCUGCAGCAGGCCUACCUCAUCAUGAUCAGUGCGCUCAUGGCCCUAGUGUUCAUCAAGUACCUCCCAGAGUGGUCCGCGUGGGUCAPCCUGGGCGCCAUCUCUGUGUAUGAUCUCGUGGCUGUGCUGUGUCCCAAAGGGCCUCUGAGAAUGCUGGUAGAAACUGCCCAGGAGAGAAAUGAGCCCAUAUUCCCUGCCCUGAUAUACUCAUCUGCCAUGGUGUGGACGGUUGGCAUGGCGAAGCUGGACCCCPCCUCUCAGGGUGCCCUCCAGCUCCCCUACGACCCGGAGAUGGAAGACUCCUAUGACAGUUUUGGGGAGCCUUCAUACCCCGAAGUCUUUGAGCCUCCCUUGACUGGCUACCCAGGGGAGGAGCUGGAGGAAGAGGAGGAAAGGGGCGUGAAGCUUGGCCUCGGGGACUUCAUCUUCUACAGUGUGCUGGUGGGCAAGGCGGCUGCCACGGGCAGCGGGGACUGGAAUACCACGCUGGCCUGCUUCGUGGCCAPCCUCAUUGGCUUGUGUCUGACCCUCCUGCUGCUUGCUGUGUUCAAGAAGGCGCUGCCCGCCCUCCCCAUCUCCAUCACGUUCGGGCUCAUCUUUUACUUCUCCACGGACAACCUGGUGCGGCCGUUCAUGGACACCCUGGCCUCCCAUCAGCUCUACAUCUGAGGGЖCAUGGUGUGCCACAGGCUGCAAGCUGCAGGGAAUUUUCAUUGGAUGCAGUUGUAUAGUUUUACACUCUAGUGCCAUAUAUUUUUAAGЖCUUUUCUUUCCUUAAAAAAUAAAGUACGUGUUUACUUGGUGAGGAGGAGGCAGAACCAGCUCUUUGGUGCCAGCUGUUUCAUCACCAGЖCUUUGGCUCCCGCUUUGGGGAGCGCCUCGCUUCACGGACAGGAAGCACAGCAGGUUUAUCCAGAUGAЖCUGAGAAGGUCAGAUUAGGGCGGGGAGAAGAGCAUCCGGCAUGAGGGCUGAGAUGCGCAAAGAGUGUGCUCGGGAGUGGCCCCUGGCACCUGGGUGCUCUGGCUGGAGAGGAAAAGCCAGUUCCCUACGAGGAGUGUUCCCAAUGCUUUGUCCAUGAUGUCCUUGUUAUUUUAUUGCCUPUAGAAACUGAGUCCUGUUCUUGUUACGGCAGUCACACUGCUGGGAAGUGGCUUAAUAGUAAUAUCAAUAAAUAGAUGA
Sequence (SHORT NAMES ENCODING)	CGGUCCCUUCCCCGGCUGUGGGUCUGCGGCCCCUGCGUGCGCAGCGCUCCUGGCCUCUGCGGCCAGCGCGGGGGCGGAGAGAGGAGAGUGCCCGGCAGGCGGCGGCUGGGCCGGCCCGGAACUGGGUCGUGGAAGGAUCGCGGGGAGCGGCCCUCAGGCCUUCGGCCUCACUGCGUCCCCACUUCCCUGCGCCCGCCUGCCGCCGAGCCCCGGCUGGGGGUGGGCGCGGCGCGAGCGGUUAAAGGGCCGGUGCAUUUAAAGGAGCGGUGCACGUGGGUCUCUGAGGCGUGUAGCAGGCGGGGGCGUUUUGUUCUUCUUCUCUCUCGCCGGAGACCUCCGUUGCGCCGAGUCCAUUCGGCCUCUAGCACCGGGUCCUGGGCAUGCUUUCCCCGGGAAGGAGGCGCGCGGGGGCUCUGCCCGCACGUGAGGGGCAGGGCCGCAGGCUCAAGCCUAGAGCCGGUUUCUGUUAGCAGCGGUGUUUGGCUGUUUUAUCAGGCAUUUCCAGCAGUGAGGAGACAGCCAGAAGCAAGCUUUUGGAGCUGAAGGAACCUGAGACAGAAGCUAGUCCCCCCUCUGAAUUUUACUGAUGAAGAAACUGAGGCCACAGAGCUAAAGUGACUUUUCCCAAGGUCGCCCAGCGAGGACGUGGGACUUCUCAGACGUCAGGAGAGUGAUGUGAGGGAGCUGUGUGACCAUAGAAAGUGACGUGUUAAAAACCAGCGCUGCCCUCUUUGAAAGCCAGGGAGCAUCAUUCAUUUAGCCUGCUGAGAAGAAGAAACCAAGUGUCCGGGAUUCAGACCUCUCUGCGGCCCCAAGUGUUCGUGGUGCUUCCAGAGGCAGGGCUAUGCUCACAUUCAUGGCCUCUGACAGCGAGGAAGAAGUGUGUGAUGAGCGGACGUCCCUAAUGUCGGCUGAGAGCCCCACGCCGCGCUCCUGCCAGGAGGGCAGGCAGGGCCCAGAGGAUGGAGAGAACACUGCCCAGUGGCCAGGAGAACGAGGAGGACGGUGAGGAGGACCCUGACCGCUAUGUCUGUAGUGGGGUUCCCGGGCGGCCGCCAGGCCUGGAGGAAGAGCUGACCCUCAAAUACGGAGCGAAGCACGUGAUCAUGCUGUUUGUGCCUGUCACUCUGUGCAUGAUCGUGGUGGUAGCCACCAUCAAGUCUGUGCGCUUCUACACAGAGAAGAAUGGACAGCUCAUCUACACGCCAUUCACUGAGGACACACCCUCGGUGGGCCAGCGCCUCCUCAACUCCGUGCUGAACACCCUCAUCAUGAUCAGCGUCAUCGUGGUUAUGACCAUCUUCUUGGUGGUGCUCUACAAGUACCGCUGCUACAAGUUCAYCCAUGGCUGGUUGAUCAUGUCUUCACUGAUGCUGCUGUUCCUCUUCACCUAUAUCUACCUUGGGGAAGUGCUCAAGACCUACAAUGUGGCCAUGGACUACCCCACCCUCUUGCUGACUGUCUGGAACUUCGGGGCAGUGGGCAUGGUGUGCAYCCACUGGAAGGGCCCUCUGGUGCUGCAGCAGGCCUACCUCAUCAUGAUCAGUGCGCUCAUGGCCCUAGUGUUCAUCAAGUACCUCCCAGAGUGGUCCGCGUGGGUCAYCCUGGGCGCCAUCUCUGUGUAUGAUCUCGUGGCUGUGCUGUGUCCCAAAGGGCCUCUGAGAAUGCUGGUAGAAACUGCCCAGGAGAGAAAUGAGCCCAUAUUCCCUGCCCUGAUAUACUCAUCUGCCAUGGUGUGGACGGUUGGCAUGGCGAAGCUGGACCCCYCCUCUCAGGGUGCCCUCCAGCUCCCCUACGACCCGGAGAUGGAAGACUCCUAUGACAGUUUUGGGGAGCCUUCAUACCCCGAAGUCUUUGAGCCUCCCUUGACUGGCUACCCAGGGGAGGAGCUGGAGGAAGAGGAGGAAAGGGGCGUGAAGCUUGGCCUCGGGGACUUCAUCUUCUACAGUGUGCUGGUGGGCAAGGCGGCUGCCACGGGCAGCGGGGACUGGAAUACCACGCUGGCCUGCUUCGUGGCCAYCCUCAUUGGCUUGUGUCUGACCCUCCUGCUGCUUGCUGUGUUCAAGAAGGCGCUGCCCGCCCUCCCCAUCUCCAUCACGUUCGGGCUCAUCUUUUACUUCUCCACGGACAACCUGGUGCGGCCGUUCAUGGACACCCUGGCCUCCCAUCAGCUCUACAUCUGAGGGm6ACAUGGUGUGCCACAGGCUGCAAGCUGCAGGGAAUUUUCAUUGGAUGCAGUUGUAUAGUUUUACACUCUAGUGCCAUAUAUUUUUAAGm6ACUUUUCUUUCCUUAAAAAAUAAAGUACGUGUUUACUUGGUGAGGAGGAGGCAGAACCAGCUCUUUGGUGCCAGCUGUUUCAUCACCAGm6ACUUUGGCUCCCGCUUUGGGGAGCGCCUCGCUUCACGGACAGGAAGCACAGCAGGUUUAUCCAGAUGAm6ACUGAGAAGGUCAGAUUAGGGCGGGGAGAAGAGCAUCCGGCAUGAGGGCUGAGAUGCGCAAAGAGUGUGCUCGGGAGUGGCCCCUGGCACCUGGGUGCUCUGGCUGGAGAGGAAAAGCCAGUUCCCUACGAGGAGUGUUCCCAAUGCUUUGUCCAUGAUGUCCUUGUUAUUUUAUUGCCUYUAGAAACUGAGUCCUGUUCUUGUUACGGCAGUCACACUGCUGGGAAGUGGCUUAAUAGUAAUAUCAAUAAAUAGAUGA
Sequence (MODOMICS CODE ENCODING)	CGGUCCCUUCCCCGGCUGUGGGUCUGCGGCCCCUGCGUGCGCAGCGCUCCUGGCCUCUGCGGCCAGCGCGGGGGCGGAGAGAGGAGAGUGCCCGGCAGGCGGCGGCUGGGCCGGCCCGGAACUGGGUCGUGGAAGGAUCGCGGGGAGCGGCCCUCAGGCCUUCGGCCUCACUGCGUCCCCACUUCCCUGCGCCCGCCUGCCGCCGAGCCCCGGCUGGGGGUGGGCGCGGCGCGAGCGGUUAAAGGGCCGGUGCAUUUAAAGGAGCGGUGCACGUGGGUCUCUGAGGCGUGUAGCAGGCGGGGGCGUUUUGUUCUUCUUCUCUCUCGCCGGAGACCUCCGUUGCGCCGAGUCCAUUCGGCCUCUAGCACCGGGUCCUGGGCAUGCUUUCCCCGGGAAGGAGGCGCGCGGGGGCUCUGCCCGCACGUGAGGGGCAGGGCCGCAGGCUCAAGCCUAGAGCCGGUUUCUGUUAGCAGCGGUGUUUGGCUGUUUUAUCAGGCAUUUCCAGCAGUGAGGAGACAGCCAGAAGCAAGCUUUUGGAGCUGAAGGAACCUGAGACAGAAGCUAGUCCCCCCUCUGAAUUUUACUGAUGAAGAAACUGAGGCCACAGAGCUAAAGUGACUUUUCCCAAGGUCGCCCAGCGAGGACGUGGGACUUCUCAGACGUCAGGAGAGUGAUGUGAGGGAGCUGUGUGACCAUAGAAAGUGACGUGUUAAAAACCAGCGCUGCCCUCUUUGAAAGCCAGGGAGCAUCAUUCAUUUAGCCUGCUGAGAAGAAGAAACCAAGUGUCCGGGAUUCAGACCUCUCUGCGGCCCCAAGUGUUCGUGGUGCUUCCAGAGGCAGGGCUAUGCUCACAUUCAUGGCCUCUGACAGCGAGGAAGAAGUGUGUGAUGAGCGGACGUCCCUAAUGUCGGCUGAGAGCCCCACGCCGCGCUCCUGCCAGGAGGGCAGGCAGGGCCCAGAGGAUGGAGAGAACACUGCCCAGUGGCCAGGAGAACGAGGAGGACGGUGAGGAGGACCCUGACCGCUAUGUCUGUAGUGGGGUUCCCGGGCGGCCGCCAGGCCUGGAGGAAGAGCUGACCCUCAAAUACGGAGCGAAGCACGUGAUCAUGCUGUUUGUGCCUGUCACUCUGUGCAUGAUCGUGGUGGUAGCCACCAUCAAGUCUGUGCGCUUCUACACAGAGAAGAAUGGACAGCUCAUCUACACGCCAUUCACUGAGGACACACCCUCGGUGGGCCAGCGCCUCCUCAACUCCGUGCUGAACACCCUCAUCAUGAUCAGCGUCAUCGUGGUUAUGACCAUCUUCUUGGUGGUGCUCUACAAGUACCGCUGCUACAAGUUCA2000000009UCCAUGGCUGGUUGAUCAUGUCUUCACUGAUGCUGCUGUUCCUCUUCACCUAUAUCUACCUUGGGGAAGUGCUCAAGACCUACAAUGUGGCCAUGGACUACCCCACCCUCUUGCUGACUGUCUGGAACUUCGGGGCAGUGGGCAUGGUGUGCA2000000009UCCACUGGAAGGGCCCUCUGGUGCUGCAGCAGGCCUACCUCAUCAUGAUCAGUGCGCUCAUGGCCCUAGUGUUCAUCAAGUACCUCCCAGAGUGGUCCGCGUGGGUCA2000000009UCCUGGGCGCCAUCUCUGUGUAUGAUCUCGUGGCUGUGCUGUGUCCCAAAGGGCCUCUGAGAAUGCUGGUAGAAACUGCCCAGGAGAGAAAUGAGCCCAUAUUCCCUGCCCUGAUAUACUCAUCUGCCAUGGUGUGGACGGUUGGCAUGGCGAAGCUGGACCCC2000000009UCCUCUCAGGGUGCCCUCCAGCUCCCCUACGACCCGGAGAUGGAAGACUCCUAUGACAGUUUUGGGGAGCCUUCAUACCCCGAAGUCUUUGAGCCUCCCUUGACUGGCUACCCAGGGGAGGAGCUGGAGGAAGAGGAGGAAAGGGGCGUGAAGCUUGGCCUCGGGGACUUCAUCUUCUACAGUGUGCUGGUGGGCAAGGCGGCUGCCACGGGCAGCGGGGACUGGAAUACCACGCUGGCCUGCUUCGUGGCCA2000000009UCCUCAUUGGCUUGUGUCUGACCCUCCUGCUGCUUGCUGUGUUCAAGAAGGCGCUGCCCGCCCUCCCCAUCUCCAUCACGUUCGGGCUCAUCUUUUACUUCUCCACGGACAACCUGGUGCGGCCGUUCAUGGACACCCUGGCCUCCCAUCAGCUCUACAUCUGAGGG2000000006ACAUGGUGUGCCACAGGCUGCAAGCUGCAGGGAAUUUUCAUUGGAUGCAGUUGUAUAGUUUUACACUCUAGUGCCAUAUAUUUUUAAG2000000006ACUUUUCUUUCCUUAAAAAAUAAAGUACGUGUUUACUUGGUGAGGAGGAGGCAGAACCAGCUCUUUGGUGCCAGCUGUUUCAUCACCAG2000000006ACUUUGGCUCCCGCUUUGGGGAGCGCCUCGCUUCACGGACAGGAAGCACAGCAGGUUUAUCCAGAUGA2000000006ACUGAGAAGGUCAGAUUAGGGCGGGGAGAAGAGCAUCCGGCAUGAGGGCUGAGAUGCGCAAAGAGUGUGCUCGGGAGUGGCCCCUGGCACCUGGGUGCUCUGGCUGGAGAGGAAAAGCCAGUUCCCUACGAGGAGUGUUCCCAAUGCUUUGUCCAUGAUGUCCUUGUUAUUUUAUUGCCU2000000009UUAGAAACUGAGUCCUGUUCUUGUUACGGCAGUCACACUGCUGGGAAGUGGCUUAAUAGUAAUAUCAAUAAAUAGAUGA

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	1342	1495	1603	1767	2020	2187	2275	2364	2432	2612
Modification Positions	Y	Y	Y	Y	Y	m6A	m6A	m6A	m6A	Y
Genomic Coordinates	1:226888095:+	1:226888918:+	1:226889026:+	1:226891319:+	1:226894118:+	1:226895583:+	1:226895671:+	1:226895760:+	1:226895828:+	1:226896008:+
Level of Experimental Evidence	3	3	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP Yfn77uLS5tv8	BtsJQJ3DteUq dknfVe6BK8aP Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP JkWoGWVwjNda Yfn77uLS5tv8	3TeAZFYFxgvp 6AyXsheySjfx 6UuHp6YApVKv aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd Mg9GixDBFQAT msuJfBpJvM5H NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP JkWoGWVwjNda Yfn77uLS5tv8	4HMi5ykupT9V Lny8GcCeVGc9 UKen6WEino9G dA7YoLwHrzgR ksEP666umrV9 ZuM5xpZmNuDL BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP iezFbUdmY3A6 JkWoGWVwjNda Yfn77uLS5tv8	3TeAZFYFxgvp 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn Lny8GcCeVGc9 BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP Mk6ShCGm6RBJ iezFbUdmY3A6 JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP Mk6ShCGm6RBJ XWZVGdLC6gGJ iezFbUdmY3A6 JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq bXBqJigD9oV3 dknfVe6BK8aP Mk6ShCGm6RBJ XWZVGdLC6gGJ iezFbUdmY3A6 JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8