General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000232424
Gene ID:	ENSG00000114315
Gene Name:	HES1
Sequence (UNICHARACTER ENCODING)	ЖCACAGGAUCCGGAGCUGGUGCUGAUAACAGCGGAAUCCCCCGUCUACCUCUCUCCUUGGUCCUGGAЖCЖGCGCUACUGAUCACCAAGUAGCCACAAAAUAUAAUAAACCCUCAGCACUUGCUCAGUAGUUUUGUGAAAGUCUCAAGUAAAAGAGACACAAACAAAAAAUUCUUUUUCGUGAAGAACUCCAAAAAUAAAAUUCUCUAGAGAUAAAAAAAAAAAAAAAAGGAAAAUGCCAGCUGAUAUAAUGGAGAAAЖAUUCCUCGUCCCCGGUGGCUGCUACCCCAGCCAGUGUCAACACGACACCGGAUAAACCAAAGACAGCAUCUGAGCACAGAAAGUCAUCAAAGCCUAUUAUGGAGAAAAGACGAAGAGCAAGAAUAAAUGAAAGUCUGAGCCAGCUGAAAACACUGAUUUUGGAUGCUCUGAAGAAAGAUAGCUCGCGGCAUUCCAAGCUGGAGAAGGCGGACAUUCUGGAAAUGACAGUGAAGCACCUCCGGAACCUGCAGCGGGCGCAGAUGACGGCUGCGCUGAGCACAGACCCAAGUGUGCUGGGGAAGUACCGAGCCGGCUUCAGCGAGUGCAUGAACGAGGUGACCCGCUUCCUGUCCACGUGCGAGGGCGUUAAUACCGAGGUGCGCACUCGGCUGCUCGGCCACCUGGCCAACUGCAUGACCCAGAUCAAUGCCAUGACCUACCCCGGGCAGCCGCACCCCGCCUUGCAGGCGCCGCCACCGCCCCCACCGGGACCCGGCGGCCCCCAGCACGCGCCGUUCGCGCCGCCGCCGCCACUCGUGCCCAPCCCCGGGGGCGCGGCGCCCCCUCCCGGCGGCGCCCCCUGCAAGCUGGGCAGCCAGGCUGGAGAGGCGGCUAAGGUGUUUGGAGGCUUCCAGGUGGUACCGGCUCCCGAUGGCCAGUUUGCUUUCCUCAUUCCCAACGGGGCCUUCGCGCACAGCGGCCCUGUCAPCCCCGUCUACACCAGCAACAGCGGCACCPCCGUGGGCCCCAACGCЖGUGUCACCUUCCAGCGGCCCCUCGCUUACGGCGGACUCCAUGUGGAGGCCGUGGCGGAACUGAGGGGGCUCAGGCCACCCCPCCUCCUAAACUCCCCAACCCACCUCUCUUCCCPCCGGЖCUCUAAACAGGAЖCUUGAAUACUGGGAGAGAAGAGGЖCUUUUUUGAUUAAGUGGUUACUUUGUGUUUUUUUAAUUUCUAAGAAGUUACUUUUUGUAGAGAGAGCUGUAUUAAGUGACUGACCAUGCACUAUAUUUGUAUAUAUUUUAUAUGUUCAUAUUGGAUUGCGCCUUUGUAUUAUAAAAGCUCAGAUGACAUUUCGUUUUUUACACGAGAUUUCUUUUUUAUGUGAUGCCAAAGAUGUUUGAAAAUGCUCUUAAAAUAUCUUCCUUUGGGGAAGUUUAUUUGAGAAAAUAUAAUAAAAGAAAAAAGUAAAGGCUUUUAUGUCUUCGAACUGAUUCUUCCAGAAUAUGUAAAAAGGCUUUUGGUGGAAUUUGAAUUACAUGUAAUUGGUAAUUCAGGAAUUGACUCUUUUGUUAUUAAAAGAACAUUUGUAAAAAUCCA
Sequence (SHORT NAMES ENCODING)	m6ACACAGGAUCCGGAGCUGGUGCUGAUAACAGCGGAAUCCCCCGUCUACCUCUCUCCUUGGUCCUGGAm6ACm6AGCGCUACUGAUCACCAAGUAGCCACAAAAUAUAAUAAACCCUCAGCACUUGCUCAGUAGUUUUGUGAAAGUCUCAAGUAAAAGAGACACAAACAAAAAAUUCUUUUUCGUGAAGAACUCCAAAAAUAAAAUUCUCUAGAGAUAAAAAAAAAAAAAAAAGGAAAAUGCCAGCUGAUAUAAUGGAGAAAm6AAUUCCUCGUCCCCGGUGGCUGCUACCCCAGCCAGUGUCAACACGACACCGGAUAAACCAAAGACAGCAUCUGAGCACAGAAAGUCAUCAAAGCCUAUUAUGGAGAAAAGACGAAGAGCAAGAAUAAAUGAAAGUCUGAGCCAGCUGAAAACACUGAUUUUGGAUGCUCUGAAGAAAGAUAGCUCGCGGCAUUCCAAGCUGGAGAAGGCGGACAUUCUGGAAAUGACAGUGAAGCACCUCCGGAACCUGCAGCGGGCGCAGAUGACGGCUGCGCUGAGCACAGACCCAAGUGUGCUGGGGAAGUACCGAGCCGGCUUCAGCGAGUGCAUGAACGAGGUGACCCGCUUCCUGUCCACGUGCGAGGGCGUUAAUACCGAGGUGCGCACUCGGCUGCUCGGCCACCUGGCCAACUGCAUGACCCAGAUCAAUGCCAUGACCUACCCCGGGCAGCCGCACCCCGCCUUGCAGGCGCCGCCACCGCCCCCACCGGGACCCGGCGGCCCCCAGCACGCGCCGUUCGCGCCGCCGCCGCCACUCGUGCCCAYCCCCGGGGGCGCGGCGCCCCCUCCCGGCGGCGCCCCCUGCAAGCUGGGCAGCCAGGCUGGAGAGGCGGCUAAGGUGUUUGGAGGCUUCCAGGUGGUACCGGCUCCCGAUGGCCAGUUUGCUUUCCUCAUUCCCAACGGGGCCUUCGCGCACAGCGGCCCUGUCAYCCCCGUCUACACCAGCAACAGCGGCACCYCCGUGGGCCCCAACGCm6AGUGUCACCUUCCAGCGGCCCCUCGCUUACGGCGGACUCCAUGUGGAGGCCGUGGCGGAACUGAGGGGGCUCAGGCCACCCCYCCUCCUAAACUCCCCAACCCACCUCUCUUCCCYCCGGm6ACUCUAAACAGGAm6ACUUGAAUACUGGGAGAGAAGAGGm6ACUUUUUUGAUUAAGUGGUUACUUUGUGUUUUUUUAAUUUCUAAGAAGUUACUUUUUGUAGAGAGAGCUGUAUUAAGUGACUGACCAUGCACUAUAUUUGUAUAUAUUUUAUAUGUUCAUAUUGGAUUGCGCCUUUGUAUUAUAAAAGCUCAGAUGACAUUUCGUUUUUUACACGAGAUUUCUUUUUUAUGUGAUGCCAAAGAUGUUUGAAAAUGCUCUUAAAAUAUCUUCCUUUGGGGAAGUUUAUUUGAGAAAAUAUAAUAAAAGAAAAAAGUAAAGGCUUUUAUGUCUUCGAACUGAUUCUUCCAGAAUAUGUAAAAAGGCUUUUGGUGGAAUUUGAAUUACAUGUAAUUGGUAAUUCAGGAAUUGACUCUUUUGUUAUUAAAAGAACAUUUGUAAAAAUCCA
Sequence (MODOMICS CODE ENCODING)	2000000006ACACAGGAUCCGGAGCUGGUGCUGAUAACAGCGGAAUCCCCCGUCUACCUCUCUCCUUGGUCCUGGA2000000006AC2000000006AGCGCUACUGAUCACCAAGUAGCCACAAAAUAUAAUAAACCCUCAGCACUUGCUCAGUAGUUUUGUGAAAGUCUCAAGUAAAAGAGACACAAACAAAAAAUUCUUUUUCGUGAAGAACUCCAAAAAUAAAAUUCUCUAGAGAUAAAAAAAAAAAAAAAAGGAAAAUGCCAGCUGAUAUAAUGGAGAAA2000000006AAUUCCUCGUCCCCGGUGGCUGCUACCCCAGCCAGUGUCAACACGACACCGGAUAAACCAAAGACAGCAUCUGAGCACAGAAAGUCAUCAAAGCCUAUUAUGGAGAAAAGACGAAGAGCAAGAAUAAAUGAAAGUCUGAGCCAGCUGAAAACACUGAUUUUGGAUGCUCUGAAGAAAGAUAGCUCGCGGCAUUCCAAGCUGGAGAAGGCGGACAUUCUGGAAAUGACAGUGAAGCACCUCCGGAACCUGCAGCGGGCGCAGAUGACGGCUGCGCUGAGCACAGACCCAAGUGUGCUGGGGAAGUACCGAGCCGGCUUCAGCGAGUGCAUGAACGAGGUGACCCGCUUCCUGUCCACGUGCGAGGGCGUUAAUACCGAGGUGCGCACUCGGCUGCUCGGCCACCUGGCCAACUGCAUGACCCAGAUCAAUGCCAUGACCUACCCCGGGCAGCCGCACCCCGCCUUGCAGGCGCCGCCACCGCCCCCACCGGGACCCGGCGGCCCCCAGCACGCGCCGUUCGCGCCGCCGCCGCCACUCGUGCCCA2000000009UCCCCGGGGGCGCGGCGCCCCCUCCCGGCGGCGCCCCCUGCAAGCUGGGCAGCCAGGCUGGAGAGGCGGCUAAGGUGUUUGGAGGCUUCCAGGUGGUACCGGCUCCCGAUGGCCAGUUUGCUUUCCUCAUUCCCAACGGGGCCUUCGCGCACAGCGGCCCUGUCA2000000009UCCCCGUCUACACCAGCAACAGCGGCACC2000000009UCCGUGGGCCCCAACGC2000000006AGUGUCACCUUCCAGCGGCCCCUCGCUUACGGCGGACUCCAUGUGGAGGCCGUGGCGGAACUGAGGGGGCUCAGGCCACCCC2000000009UCCUCCUAAACUCCCCAACCCACCUCUCUUCCC2000000009UCCGG2000000006ACUCUAAACAGGA2000000006ACUUGAAUACUGGGAGAGAAGAGG2000000006ACUUUUUUGAUUAAGUGGUUACUUUGUGUUUUUUUAAUUUCUAAGAAGUUACUUUUUGUAGAGAGAGCUGUAUUAAGUGACUGACCAUGCACUAUAUUUGUAUAUAUUUUAUAUGUUCAUAUUGGAUUGCGCCUUUGUAUUAUAAAAGCUCAGAUGACAUUUCGUUUUUUACACGAGAUUUCUUUUUUAUGUGAUGCCAAAGAUGUUUGAAAAUGCUCUUAAAAUAUCUUCCUUUGGGGAAGUUUAUUUGAGAAAAUAUAAUAAAAGAAAAAAGUAAAGGCUUUUAUGUCUUCGAACUGAUUCUUCCAGAAUAUGUAAAAAGGCUUUUGGUGGAAUUUGAAUUACAUGUAAUUGGUAAUUCAGGAAUUGACUCUUUUGUUAUUAAAAGAACAUUUGUAAAAAUCCA

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected. Class 4 is considered as questionable. Class 5 evidence means that verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences. Edit locations not originally present in the RNA sequences are marked by their source. Their scores are in third row.}

Position in the Sequence	1	68	70	258	802	967	996	1013	1095	1128	1133	1146	1170
Modification Positions	m6A	m6A	m6A	m6A	Y	Y	Y	m6A	Y	Y	m6A	m6A	m6A
Genomic Coordinates	3:194136148:+	3:194136215:+	3:194136217:+	3:194136405:+	3:194137959:+	3:194138124:+	3:194138153:+	3:194138170:+	3:194138252:+	3:194138285:+	3:194138290:+	3:194138303:+	3:194138327:+
Level of Experimental Evidence	3	3	3	3	3	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	3TeAZFYFxgvp 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn	BtsJQJ3DteUq eGNFqdoGxzRm oZ9Kp5NX8Hv5 XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac Yfn77uLS5tv8	834aFpha8RvT dA7YoLwHrzgR ksEP666umrV9 ZuM5xpZmNuDL	834aFpha8RvT dA7YoLwHrzgR ksEP666umrV9 ZuM5xpZmNuDL	BtsJQJ3DteUq eGNFqdoGxzRm iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq eGNFqdoGxzRm kx7BHU7ZycYE iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq eGNFqdoGxzRm kx7BHU7ZycYE iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	834aFpha8RvT dA7YoLwHrzgR ksEP666umrV9 ZuM5xpZmNuDL	BtsJQJ3DteUq eGNFqdoGxzRm XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	BtsJQJ3DteUq eGNFqdoGxzRm kx7BHU7ZycYE XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3TeAZFYFxgvp 4HMi5ykupT9V 5aTkEfEpX8Xm 5FhTyQVy2tKW 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gBgcfFQ5WN9C gZuvgwMuBfgh jNkxUQNx8GRd KRfQJWH4K5KH Mg9GixDBFQAT msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn 93arJtwJmuS9 BkoLW2CBToyL nfCHyrYzE6fB Lny8GcCeVGc9 UKen6WEino9G BtsJQJ3DteUq eGNFqdoGxzRm kx7BHU7ZycYE XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	3TeAZFYFxgvp 4HMi5ykupT9V 5aTkEfEpX8Xm 5Nnepx5V7yHo 6AyXsheySjfx 6UuHp6YApVKv aHkqKEJkRYyb aivdrAsbdKEU Ap2q43bQLNek gZuvgwMuBfgh jNkxUQNx8GRd msuJfBpJvM5H nGifePrmgHfe NjZ8bGGJsNSR Q36pf44ZRvxu QmcpiJ88DBDn QpiKdbVikVz2 UN3tNpbCPHYf V5PvfiKsgFMd VL7zkHvkfkoB VyCX26p5UBRL WdHxkJGRmFxn BtsJQJ3DteUq eGNFqdoGxzRm kx7BHU7ZycYE XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8	4HMi5ykupT9V 5aTkEfEpX8Xm 6UuHp6YApVKv jNkxUQNx8GRd msuJfBpJvM5H VyCX26p5UBRL BkoLW2CBToyL nfCHyrYzE6fB Lny8GcCeVGc9 BtsJQJ3DteUq eGNFqdoGxzRm kx7BHU7ZycYE XWZVGdLC6gGJ iezFbUdmY3A6 S9vNeQQYrhac JkWoGWVwjNda a7o5Kmjr4Tdp Yfn77uLS5tv8