Modomics - A Database of RNA Modifications

General Data

RNA Type	mRNA
Original Source	Sci-ModoM
Transcript ID:	ENST00000341441
Gene ID:	ENSG00000106484
Gene Name:	MEST
Sequence (UNICHARACTER ENCODING)	AGGUGGCGCUGACGCCUGGCAGGGAGAAGGCGGCAGCACAUGCUGGGCUCGGGGGCGAUGGGCUUGUGCGCGGACCUGGCGACGCUCUAGCCCCGAGCCGCGUAUUCGUGGCCGGGUCCUCCCUGGGAACAGGGUGAAGGCCGAGAACCUCUGGCCUCAGGAAGCGCAUGCGCAACCGGUUCUCCGAAACAUGGAGUCCUGUAGGCAAGGUCUUACCUGAAUCAGGAUGAGGGAGUGGUGGGUCCAGGUGGGGCUGCUGGCCGUGCCCCUGCUUGCUGCGUACCUGCACAPCCCACCCCCUCAGCUCUCCCCUGCCCUUCACUCAUGGAAGUCUUCAGGCAAGUUUUUCACUUACЖAGGGACUGCGUAUCUUCUACCAAGACUCUGUGGGUGUGGUUGGAAGUCCAGAGAUAGUUGUGCUUUUACACGGUUUUCCAACAPCCAGCUACGACUGGUACAAGAUUUGGGAAGGUCUGACCUUGAGGUUUCAUCGGGUGAUUGCCCUUGAUUUCUUAGGCUUUGGCUUCAGUGACAAЖCCGAGACCACAUCACUAUUCCAUAUPUGAGCAGGCCAGCAUCGUGGAAGCGCUUUUGCGGCAUCUGGGGCUCCAGAACCGCAGGAUCAACCUUCUUUCUCAUGACUAUGGAGAUAUUGUUGCUCAGGAGCUUCUCUACAGGUACAAGCAGAAUCGAUCUGGUCGGCUUACCAUAAAGAGUCUCUGUCUGUCAAAUGGAGGUAUCUUUCCUGAGACUCACCGUCCACUCCUUCUCCAAAAGCUACUCAAAGAUGGAGGUGUGCUGUCACCCAPCCUCACACGACUGAUGAACUUCUUUGUAUUCUCUCGAGGUCUCACCCCAGUCUUUGGGCCGUAUACUCGGCCCUCUGAGAGUGAGCUGUGGGACAUGUGGGCAGGGAUCCGCAACAAUGACGGGAACUUAGUCAUUGACAGUCUCUUACAGUACAUCAAUCAGAGGAAGAAGUUCAGAAGGCGCUGGGUGGGAGCUCUUGCCUCUGUAACUAUCCCCAUUCAUUUUAUCUAUGGGCCAUUGGAUCCUGUAAAUCCCUAUCCAGAGUUUUUGGAGCUGUACAGGAAAACGCUGCCGCGGUCCACAGUGUCGAUUCUGGAUGACCACAUUAGCCACUAUCCACAGCUAGAGGAUCCCAUGGGCUUCUUGAAUGCAUAUAUGGGCUUCAUCAACUCCUUCUGAGCUGGAAAGAGUAGCUUCCCUGUAUUACCUCCCCUACUCCCUUAUGUGUUGUGUAUUCCACUUAGGAAGAAAUGCCCAAAAGAGGUCCUGGCCAUCAAACAUAAUUCUCUCACAAAGUCCACUPUACUCAAAUUGGUGAЖCAGUGUAUAGGAAGAAGCCAGCAGGAGCUCUGACUAAGGUUGACAUAAUAGUCCACCUCCCAUUACUUUGAUAUCUGAUCAAAUGUAUAGACUUGGCUUUGUUUUUUGUGCUAUUAGGAAAUUCUGAUGAGCAUUACUAUUCACUGAUGCAGAAAGACGUUCUUUUGCAUAAAAGACUUUUUUUUAЖCACUUUGGACUUCUCUGAAAUAUUUAGAAGUGCUAAUUUCUGGCCCACCCCCAACAGGAAUUCUAUAGUAAGGAGGAGGAGAAGGGGGGCUCCUUCCCUCUCCUCGAAUGACGUUAUGGGCACAUGCCUUUUAAAAGUUCUPUAAGCAACACAGAGCUGAGUCCUCUUUGUCAUACCUUUGGAUUUAGUGUUUCAUCAGCUGUUUUUAGUUAUAAЖCAUUUUGUUAAAAUAGAUAUUGGUUUAAAUGAUACЖGUAUUUUAGGUAUGAUUUAAGACUAUGAUUUACCUAUACAUUAUAUAUAUUUUAUAAAGAUACUAAACCAGCAUACCCUUACUCUGCCAGAGUAGUGAAGCUAAUUAAACACAUUUGGUUUCUGAAUAAAUUGAACUAAAUCCAAACUAUUUCCUAAAAUCACAGGACAUUAAGGACCAAUAGCAUCUGUGCCAGAGAUGUACUGUUAUUAGCUGGGAAGACCAAUUCUAACAGCAAAUAACAGUCUGAGACUCCUCAUACCUCAGUGGUUAGAAGCAUGUCUCUCUUGAGCUACAGUAGAGGGGAAGGGAUUGUUGUGUAGUCAAGUCACCAUGCUGAAUGUACЖCUGAUUCCUPUAUGAUGACUGCUUAЖCUCCCCACUGCCUGUCCCAGAGAGGCUUUCCAAUGUAGCUCAGUAAUUCCUGUUACUPUACAGACAGGAAAGUUCCAGAAACUPUAAGAACAAACUCUGAAAGACCUAUGAGCAAAUGGUGCUGAAUACUUUUUUUUUAAAGCCACAUUUCAUUGUCUUAGUCAAAGCAGGAUUAUUAAGUGAUUAUUUAAAAUUCGUUUUUUUAAAUUAGCAACUUCAAGUAUAACAACUUUGAAACUGGAAUAAGUGUUUAUUUUCUAUUAAUAAAAAUGAAUUGUGACAAAA
Sequence (SHORT NAMES ENCODING)	AGGUGGCGCUGACGCCUGGCAGGGAGAAGGCGGCAGCACAUGCUGGGCUCGGGGGCGAUGGGCUUGUGCGCGGACCUGGCGACGCUCUAGCCCCGAGCCGCGUAUUCGUGGCCGGGUCCUCCCUGGGAACAGGGUGAAGGCCGAGAACCUCUGGCCUCAGGAAGCGCAUGCGCAACCGGUUCUCCGAAACAUGGAGUCCUGUAGGCAAGGUCUUACCUGAAUCAGGAUGAGGGAGUGGUGGGUCCAGGUGGGGCUGCUGGCCGUGCCCCUGCUUGCUGCGUACCUGCACAYCCCACCCCCUCAGCUCUCCCCUGCCCUUCACUCAUGGAAGUCUUCAGGCAAGUUUUUCACUUACm6AAGGGACUGCGUAUCUUCUACCAAGACUCUGUGGGUGUGGUUGGAAGUCCAGAGAUAGUUGUGCUUUUACACGGUUUUCCAACAYCCAGCUACGACUGGUACAAGAUUUGGGAAGGUCUGACCUUGAGGUUUCAUCGGGUGAUUGCCCUUGAUUUCUUAGGCUUUGGCUUCAGUGACAAm6ACCGAGACCACAUCACUAUUCCAUAUYUGAGCAGGCCAGCAUCGUGGAAGCGCUUUUGCGGCAUCUGGGGCUCCAGAACCGCAGGAUCAACCUUCUUUCUCAUGACUAUGGAGAUAUUGUUGCUCAGGAGCUUCUCUACAGGUACAAGCAGAAUCGAUCUGGUCGGCUUACCAUAAAGAGUCUCUGUCUGUCAAAUGGAGGUAUCUUUCCUGAGACUCACCGUCCACUCCUUCUCCAAAAGCUACUCAAAGAUGGAGGUGUGCUGUCACCCAYCCUCACACGACUGAUGAACUUCUUUGUAUUCUCUCGAGGUCUCACCCCAGUCUUUGGGCCGUAUACUCGGCCCUCUGAGAGUGAGCUGUGGGACAUGUGGGCAGGGAUCCGCAACAAUGACGGGAACUUAGUCAUUGACAGUCUCUUACAGUACAUCAAUCAGAGGAAGAAGUUCAGAAGGCGCUGGGUGGGAGCUCUUGCCUCUGUAACUAUCCCCAUUCAUUUUAUCUAUGGGCCAUUGGAUCCUGUAAAUCCCUAUCCAGAGUUUUUGGAGCUGUACAGGAAAACGCUGCCGCGGUCCACAGUGUCGAUUCUGGAUGACCACAUUAGCCACUAUCCACAGCUAGAGGAUCCCAUGGGCUUCUUGAAUGCAUAUAUGGGCUUCAUCAACUCCUUCUGAGCUGGAAAGAGUAGCUUCCCUGUAUUACCUCCCCUACUCCCUUAUGUGUUGUGUAUUCCACUUAGGAAGAAAUGCCCAAAAGAGGUCCUGGCCAUCAAACAUAAUUCUCUCACAAAGUCCACUYUACUCAAAUUGGUGAm6ACAGUGUAUAGGAAGAAGCCAGCAGGAGCUCUGACUAAGGUUGACAUAAUAGUCCACCUCCCAUUACUUUGAUAUCUGAUCAAAUGUAUAGACUUGGCUUUGUUUUUUGUGCUAUUAGGAAAUUCUGAUGAGCAUUACUAUUCACUGAUGCAGAAAGACGUUCUUUUGCAUAAAAGACUUUUUUUUAm6ACACUUUGGACUUCUCUGAAAUAUUUAGAAGUGCUAAUUUCUGGCCCACCCCCAACAGGAAUUCUAUAGUAAGGAGGAGGAGAAGGGGGGCUCCUUCCCUCUCCUCGAAUGACGUUAUGGGCACAUGCCUUUUAAAAGUUCUYUAAGCAACACAGAGCUGAGUCCUCUUUGUCAUACCUUUGGAUUUAGUGUUUCAUCAGCUGUUUUUAGUUAUAAm6ACAUUUUGUUAAAAUAGAUAUUGGUUUAAAUGAUACm6AGUAUUUUAGGUAUGAUUUAAGACUAUGAUUUACCUAUACAUUAUAUAUAUUUUAUAAAGAUACUAAACCAGCAUACCCUUACUCUGCCAGAGUAGUGAAGCUAAUUAAACACAUUUGGUUUCUGAAUAAAUUGAACUAAAUCCAAACUAUUUCCUAAAAUCACAGGACAUUAAGGACCAAUAGCAUCUGUGCCAGAGAUGUACUGUUAUUAGCUGGGAAGACCAAUUCUAACAGCAAAUAACAGUCUGAGACUCCUCAUACCUCAGUGGUUAGAAGCAUGUCUCUCUUGAGCUACAGUAGAGGGGAAGGGAUUGUUGUGUAGUCAAGUCACCAUGCUGAAUGUACm6ACUGAUUCCUYUAUGAUGACUGCUUAm6ACUCCCCACUGCCUGUCCCAGAGAGGCUUUCCAAUGUAGCUCAGUAAUUCCUGUUACUYUACAGACAGGAAAGUUCCAGAAACUYUAAGAACAAACUCUGAAAGACCUAUGAGCAAAUGGUGCUGAAUACUUUUUUUUUAAAGCCACAUUUCAUUGUCUUAGUCAAAGCAGGAUUAUUAAGUGAUUAUUUAAAAUUCGUUUUUUUAAAUUAGCAACUUCAAGUAUAACAACUUUGAAACUGGAAUAAGUGUUUAUUUUCUAUUAAUAAAAAUGAAUUGUGACAAAA
Sequence (MODOMICS CODE ENCODING)	AGGUGGCGCUGACGCCUGGCAGGGAGAAGGCGGCAGCACAUGCUGGGCUCGGGGGCGAUGGGCUUGUGCGCGGACCUGGCGACGCUCUAGCCCCGAGCCGCGUAUUCGUGGCCGGGUCCUCCCUGGGAACAGGGUGAAGGCCGAGAACCUCUGGCCUCAGGAAGCGCAUGCGCAACCGGUUCUCCGAAACAUGGAGUCCUGUAGGCAAGGUCUUACCUGAAUCAGGAUGAGGGAGUGGUGGGUCCAGGUGGGGCUGCUGGCCGUGCCCCUGCUUGCUGCGUACCUGCACA2000000009UCCCACCCCCUCAGCUCUCCCCUGCCCUUCACUCAUGGAAGUCUUCAGGCAAGUUUUUCACUUAC2000000006AAGGGACUGCGUAUCUUCUACCAAGACUCUGUGGGUGUGGUUGGAAGUCCAGAGAUAGUUGUGCUUUUACACGGUUUUCCAACA2000000009UCCAGCUACGACUGGUACAAGAUUUGGGAAGGUCUGACCUUGAGGUUUCAUCGGGUGAUUGCCCUUGAUUUCUUAGGCUUUGGCUUCAGUGACAA2000000006ACCGAGACCACAUCACUAUUCCAUAU2000000009UUGAGCAGGCCAGCAUCGUGGAAGCGCUUUUGCGGCAUCUGGGGCUCCAGAACCGCAGGAUCAACCUUCUUUCUCAUGACUAUGGAGAUAUUGUUGCUCAGGAGCUUCUCUACAGGUACAAGCAGAAUCGAUCUGGUCGGCUUACCAUAAAGAGUCUCUGUCUGUCAAAUGGAGGUAUCUUUCCUGAGACUCACCGUCCACUCCUUCUCCAAAAGCUACUCAAAGAUGGAGGUGUGCUGUCACCCA2000000009UCCUCACACGACUGAUGAACUUCUUUGUAUUCUCUCGAGGUCUCACCCCAGUCUUUGGGCCGUAUACUCGGCCCUCUGAGAGUGAGCUGUGGGACAUGUGGGCAGGGAUCCGCAACAAUGACGGGAACUUAGUCAUUGACAGUCUCUUACAGUACAUCAAUCAGAGGAAGAAGUUCAGAAGGCGCUGGGUGGGAGCUCUUGCCUCUGUAACUAUCCCCAUUCAUUUUAUCUAUGGGCCAUUGGAUCCUGUAAAUCCCUAUCCAGAGUUUUUGGAGCUGUACAGGAAAACGCUGCCGCGGUCCACAGUGUCGAUUCUGGAUGACCACAUUAGCCACUAUCCACAGCUAGAGGAUCCCAUGGGCUUCUUGAAUGCAUAUAUGGGCUUCAUCAACUCCUUCUGAGCUGGAAAGAGUAGCUUCCCUGUAUUACCUCCCCUACUCCCUUAUGUGUUGUGUAUUCCACUUAGGAAGAAAUGCCCAAAAGAGGUCCUGGCCAUCAAACAUAAUUCUCUCACAAAGUCCACU2000000009UUACUCAAAUUGGUGA2000000006ACAGUGUAUAGGAAGAAGCCAGCAGGAGCUCUGACUAAGGUUGACAUAAUAGUCCACCUCCCAUUACUUUGAUAUCUGAUCAAAUGUAUAGACUUGGCUUUGUUUUUUGUGCUAUUAGGAAAUUCUGAUGAGCAUUACUAUUCACUGAUGCAGAAAGACGUUCUUUUGCAUAAAAGACUUUUUUUUA2000000006ACACUUUGGACUUCUCUGAAAUAUUUAGAAGUGCUAAUUUCUGGCCCACCCCCAACAGGAAUUCUAUAGUAAGGAGGAGGAGAAGGGGGGCUCCUUCCCUCUCCUCGAAUGACGUUAUGGGCACAUGCCUUUUAAAAGUUCU2000000009UUAAGCAACACAGAGCUGAGUCCUCUUUGUCAUACCUUUGGAUUUAGUGUUUCAUCAGCUGUUUUUAGUUAUAA2000000006ACAUUUUGUUAAAAUAGAUAUUGGUUUAAAUGAUAC2000000006AGUAUUUUAGGUAUGAUUUAAGACUAUGAUUUACCUAUACAUUAUAUAUAUUUUAUAAAGAUACUAAACCAGCAUACCCUUACUCUGCCAGAGUAGUGAAGCUAAUUAAACACAUUUGGUUUCUGAAUAAAUUGAACUAAAUCCAAACUAUUUCCUAAAAUCACAGGACAUUAAGGACCAAUAGCAUCUGUGCCAGAGAUGUACUGUUAUUAGCUGGGAAGACCAAUUCUAACAGCAAAUAACAGUCUGAGACUCCUCAUACCUCAGUGGUUAGAAGCAUGUCUCUCUUGAGCUACAGUAGAGGGGAAGGGAUUGUUGUGUAGUCAAGUCACCAUGCUGAAUGUAC2000000006ACUGAUUCCU2000000009UUAUGAUGACUGCUUA2000000006ACUCCCCACUGCCUGUCCCAGAGAGGCUUUCCAAUGUAGCUCAGUAAUUCCUGUUACU2000000009UUACAGACAGGAAAGUUCCAGAAACU2000000009UUAAGAACAAACUCUGAAAGACCUAUGAGCAAAUGGUGCUGAAUACUUUUUUUUUAAAGCCACAUUUCAUUGUCUUAGUCAAAGCAGGAUUAUUAAGUGAUUAUUUAAAAUUCGUUUUUUUAAAUUAGCAACUUCAAGUAUAACAACUUUGAAACUGGAAUAAGUGUUUAUUUUCUAUUAAUAAAAAUGAAUUGUGACAAAA

Score Table

_{Table containing the score explanation. Score identify the level of experimental reliability and
evidence so as exaplained in the 2023 release manuscript. Class 1 should be considered
as highlyrelevant. Class 2 evidences are considered as Solid, namely large errors are unlikely and minor errors
should not undermine the meaning of data. Class 3 is considered as speculative and errors are expected.
Class 4 is considered as questionable. Class 5 evidence means that
verification and data are still to be collected. Class 6 data cannot be estimated.}

Method Classification	Score
Multiple direct experimental evidence	1
Direct experimental evidence	2
Inferred based on indirect experimental evidence	3
Predicted computationally	4
Evidence not yet annotated (Unknown)	5
Irrelevant	6

Modification Positions

_{Table containing the original modifications present in the MODOMICS sequences.
Edit locations not originally present in the RNA sequences are marked by their source.
Their scores are in third row.}

Position in the Sequence	291	356	440	535	561	807	1331	1347	1534	1676	1750	1786	2132	2142	2158	2216	2242
Modification Positions	Y	m6A	Y	m6A	Y	Y	Y	m6A	m6A	Y	m6A	m6A	m6A	Y	m6A	Y	Y
Genomic Coordinates	7:130495433:+	7:130495498:+	7:130497215:+	7:130498010:+	7:130498161:+	7:130500493:+	7:130505180:+	7:130505196:+	7:130505383:+	7:130505525:+	7:130505599:+	7:130505635:+	7:130505981:+	7:130505991:+	7:130506007:+	7:130506065:+	7:130506091:+
Level of Experimental Evidence	3	3	3	3	3	3	3	3	3	3	3	3	3	3	3	3	3
Level of Experimental Reliability	3	3	3	3	3	3	3	3	3	3	3	3	3	3	3	3	3
Source	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM	Sci-ModoM
EUFIDs	bXBqJigD9oV3 f6YSioLdAWpr	3kRDPWwiRCgi L6w2k2VEv4EY	bXBqJigD9oV3 eGNFqdoGxzRm f6YSioLdAWpr	bXBqJigD9oV3 eGNFqdoGxzRm f6YSioLdAWpr	bXBqJigD9oV3 eGNFqdoGxzRm f6YSioLdAWpr	bXBqJigD9oV3 eGNFqdoGxzRm f6YSioLdAWpr	bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr	bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE	bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE	bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE	bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE	3kRDPWwiRCgi L6w2k2VEv4EY	3kRDPWwiRCgi L6w2k2VEv4EY	bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE	bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE	bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE	bXBqJigD9oV3 dknfVe6BK8aP eGNFqdoGxzRm f6YSioLdAWpr kx7BHU7ZycYE