Name | Breast cancer (N:Nm) |
Description | Methylation levels on 5.8S, 18S, and 28S rRNAs are slightly increasing in p53 knock-downs. |
Related RNA reaction | N:Nm |
Found in RNA | rRNA |
Modified Transcript | |
Mapping Technology | |
Quantification techniques | site-specific semiquantitative RT-qPCR based method |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
FBL | rRNA 2′-O-methyltransferase fibrillarin | oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
981 | p53 acts as a safeguard of translational control by regulating fibrillarin and rRNAmethylation in cancer. | Marcel V, Ghayad SE, Belin S, Therizols G, Morel AP, Solano-Gonzàlez E, Vendrell JA, Hacot S, Mertani HC, Albaret MA, Bourdon JC, Jordan L, Thompson A, Tafer Y, Cong R, Bouvet P, Saurin JC, Catez F, Prats AC, Puisieux A, Diaz JJ | Cancer Cell | [details] | 24029231 | S1535-6108(13)00359-0 |