Modomics - A Database of RNA Modifications

Summary:

NameBreast cancer (N:Nm)
DescriptionMethylation levels on 5.8S, 18S, and 28S rRNAs are slightly increasing in p53 knock-downs.
Related RNA reactionN:Nm
Found in RNArRNA
Modified Transcript
Mapping Technology
Quantification techniquessite-specific semiquantitative RT-qPCR based method

Enzymes connected to Breast cancer:

Acronym Full name Enzyme Role Organism Comment
FBL rRNA 2′-O-methyltransferase fibrillarin oncogene Homo sapiens

Publications:

ID Title Authors Journal Details PubMed Id DOI
981 p53 acts as a safeguard of translational control by regulating fibrillarin and rRNAmethylation in cancer. Marcel V, Ghayad SE, Belin S, Therizols G, Morel AP, Solano-Gonzàlez E, Vendrell JA, Hacot S, Mertani HC, Albaret MA, Bourdon JC, Jordan L, Thompson A, Tafer Y, Cong R, Bouvet P, Saurin JC, Catez F, Prats AC, Puisieux A, Diaz JJ Cancer Cell [details] 24029231 S1535-6108(13)00359-0