Summary:

NameBreast cancer (xX:Xm)
DescriptionMethylation levels on 5.8S, 18S, and 28S rRNAs are slightly increasing in p53 knock-downs.
Related RNA reactionxX:Xm
Found in RNArRNA
Modified Transcript
Mapping Technology
Quantification techniquessite-specific semiquantitative RT-qPCR based method

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
FBL rRNA 2′-O-methyltransferase fibrillarin oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
981 p53 acts as a safeguard of translational control by regulating fibrillarin and rRNAmethylation in cancer. Marcel V Cancer Cell [details] 24029231 S1535-6108(13)00359-0

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