Name | Cancer (not specified) (A:m1A) |
Description | Demethylated tRNA is more sensitive to angiogenin that mediates the cleavage of tRNAs, so tRNA-derived small RNAs are involved in ALKBH3-induced cancer progression by preventing apoptosis of cancer cells. |
Related RNA reaction | A:m1A |
Found in RNA | tRNA |
Modified Transcript | None |
Mapping Technology | CLIP-seq |
Quantification techniques | LC–MS/MS |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
ALKBH4 | alkB homolog 4, lysine demethylase | oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
990 | Transfer RNA demethylase ALKBH3 promotes cancer progression via induction oftRNA-derived small RNAs. | Chen Z | Nucleic Acids Res | [details] | 30541109 | 5239036 |