Modomics - A Database of RNA Modifications

Summary:

NameCervical cancer (A:I)
DescriptionThe two edited forms of BLCAP fail to inhibit STAT3 phosphorylation. A-to-I RNA editing drives anti-tumorigenic BLCAP into a loss-of-function state that might facilitate the events leading to cervical cancer initiation, and progression
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptBLCAP
Mapping TechnologyMiseq-sequencing, pyrosequencing
Quantification techniquesRT-PCR, Co-IP

Enzymes connected to Cervical cancer:

Acronym Full name Enzyme Role Organism Comment
ADAR Double-stranded RNA-specific adenosine deaminase tumor-suppressor/oncogene Homo sapiens

Publications:

ID Title Authors Journal Details PubMed Id DOI
996 A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervicalcancer. Chen W, He W, Cai H, Hu B, Zheng C, Ke X, Xie L, Zheng Z, Wu X, Wang H Oncotarget [details] 28455960 17034