Name | Cervical cancer (A:I) |
Description | The two edited forms of BLCAP fail to inhibit STAT3 phosphorylation. A-to-I RNA editing drives anti-tumorigenic BLCAP into a loss-of-function state that might facilitate the events leading to cervical cancer initiation, and progression |
Related RNA reaction | A:I |
Found in RNA | mRNA |
Modified Transcript | BLCAP |
Mapping Technology | Miseq-sequencing, pyrosequencing |
Quantification techniques | RT-PCR, Co-IP |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
ADAR | Double-stranded RNA-specific adenosine deaminase | tumor-suppressor/oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
996 | A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervicalcancer. | Chen W | Oncotarget | [details] | 28455960 | 17034 |