Modomics - A Database of RNA Modifications

Reaction details:

Reaction type level 1: deamination
Reaction type level 2: NH2/O exchange
Reaction type level 3: group exchange
Input group: NH2
Output group: *=O
Introduced group name: oxo
Introduced group type: oxo
Site: base/endocyclic
Atom address: C6
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
ADAR Double-stranded RNA-specific adenosine deaminase Homo sapiens
ADARB1 Double-stranded RNA-specific editase 1 Homo sapiens
ADAT2 adenosine deaminase, tRNA specific 2 Homo sapiens
ADAT3 Probable inactive tRNA-specific adenosine deaminase-like protein 3 Homo sapiens
Tad1 tRNA-specific adenosine deaminase 1 Saccharomyces cerevisiae
Tad1 tRNA-specific adenosine deaminase 1 Homo sapiens
Tad2 tRNA-specific adenosine deaminase subunit TAD2 Saccharomyces cerevisiae
Tad3 tRNA-specific adenosine deaminase subunit TAD3 Saccharomyces cerevisiae
TadA tRNA-specific adenosine deaminase Escherichia coli
TadA tRNA-specific adenosine deaminase, chloroplastic Arabidopsis thaliana

Image with reaction


Title Authors Journal Details PubMed Id DOI
Determinants of tRNA editing and modification: Avoiding conundrums, affecting function. Paris Z, Fleming IM, Alfonzo JD Semin Cell Dev Biol [details] 22024020 -