Summary:

NameCervical cancer (A:I)
DescriptionThe two edited forms of BLCAP fail to inhibit STAT3 phosphorylation indicating that A-to-I RNA editing drive anti-tumorigenic BLCAP to a loss-of-function one which might facilitate the cervical cancer initiating and progressing events
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptBLCAP
Mapping TechnologyMiseq-sequencing, pyrosequencing
Quantification techniquesRT-PCR, Co-IP

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
ADARB1 Double-stranded RNA-specific editase 1 tumor-suppressor/oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
996 A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervicalcancer. Chen W Oncotarget [details] 28455960 17034

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