Name | Cervical cancer (A:I) |
Description | The two edited forms of BLCAP fail to inhibit STAT3 phosphorylation indicating that A-to-I RNA editing drive anti-tumorigenic BLCAP to a loss-of-function one which might facilitate the cervical cancer initiating and progressing events |
Related RNA reaction | A:I |
Found in RNA | mRNA |
Modified Transcript | BLCAP |
Mapping Technology | Miseq-sequencing, pyrosequencing |
Quantification techniques | RT-PCR, Co-IP |
Acronym | Full name | Enzyme Role | Organism |
---|---|---|---|
ADARB1 | Double-stranded RNA-specific editase 1 | tumor-suppressor/oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
996 | A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervicalcancer. | Chen W | Oncotarget | [details] | 28455960 | 17034 |