Modomics - A Database of RNA Modifications

Summary:

NameCervical cancer (A:I)
DescriptionThe two edited forms of BLCAP fail to inhibit STAT3 phosphorylation. A-to-I RNA editing drives anti-tumorigenic BLCAP into a loss-of-function state that might facilitate the events leading to cervical cancer initiation, and progression
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptBLCAP
Mapping TechnologyMiseq-sequencing, pyrosequencing
Quantification techniquesRT-PCR, Co-IP

Enzymes connected to Cervical cancer:

Acronym Full name Enzyme Role Organism Comment
ADAR Double-stranded RNA-specific adenosine deaminase tumor-suppressor/oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
996 A-to-I RNA editing of BLCAP lost the inhibition to STAT3 activation in cervicalcancer. Chen W Oncotarget [details] 28455960 17034