|Depression disorder (A:I)
|RNA editing inhibits the enzymatic activity of TPH2 splice variants. Deregulated alternative splicing and RNA editing are involved in the etiology of psychiatric diseases, such as suicidal behavior.
|Related RNA reaction
|Found in RNA
|Exact modification enzyme yet to be verified. One or more ADAR enzymes involved, putatively.
|Alternative splicing and extensive RNA editing of human TPH2 transcripts.