Name | Depression disorder (C:U) |
Description | RNA editing inhibits the enzymatic activity of TPH2 splice variants. Deregulated alternative splicing and RNA editing are involved in the etiology of psychiatric diseases, such as suicidal behavior. |
Related RNA reaction | C:U |
Found in RNA | mRNA |
Modified Transcript | TPH2a |
Mapping Technology | exone sequencing |
Quantification techniques | HPLC |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
ADARB1 | Double-stranded RNA-specific editase 1 | None | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1008 | Alternative splicing and extensive RNA editing of human TPH2 transcripts. | Maik Grohmann | PLoS One | [details] | 20126463 | 10.1371/journal.pone.0008956 |