| Name | Gastric cancer (A:m6A) |
| Description | ALKBH5 and NEAT1 are upregulated in gastric cancer. The m6A eraser ALKBH5 downregulates NEAT1 m6A levels. With decreases in NEAT1 methylation, NEAT1 is upregulated and promotes the malignant phenotype of GC by acting synergistically with EZH2 |
| Related RNA reaction | A:m6A |
| Found in RNA | lncRNA |
| Modified Transcript | NEAT1 |
| Mapping Technology | |
| Quantification techniques | MeRIP-RT-PCR |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| ALKBH5 | RNA demethylase ALKBH5 | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1017 | ALKBH5 promotes invasion and metastasis of gastric cancer by decreasing methylation of the lncRNA NEAT1. | Jun Zhang | J Physiol Biochem | [details] | 31290116 | 10.1007/s13105-019-00690-8 |