Modomics - A Database of RNA Modifications

Summary:

NameMyeloma (A:I)
DescriptionDeregulation GLI1 RNA editing is correlated to multiple myeloma
Related RNA reactionA:I
Found in RNAmRNA
Modified TranscriptGLI1
Mapping TechnologySanger sequencing
Quantification techniquesqPCR

Enzymes connected to Myeloma:

Acronym Full name Enzyme Role Organism Comment
ADAR Double-stranded RNA-specific adenosine deaminase oncogene Homo sapiens

Publications:

ID Title Authors Journal Details PubMed Id DOI
1081 Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma. Phoebe K Mondala,Nathaniel Delos Santos,Amber C Miller,Gabriel Pineda,Qingfei Jiang,Heather Leu,Shawn A Ali,Anusha-Preethi Ganesan,Christina N Wu,Caitlin Costello,Mark Minden,Raffaella Chiaramonte,A Keith Stewart,Leslie A Crews, Nat Commun [details] 29203771 10.1038/s41467-017-01890-w