Name | Neurofibromatosis (C:U) |
Description | C→U editing of NF1 RNA creates a translational stop codon, potentially leading to premature truncation of neurofibromin |
Related RNA reaction | C:U |
Found in RNA | mRNA |
Modified Transcript | NF1 |
Mapping Technology | Direct sequencing |
Quantification techniques | RT-PCR |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
APOBEC1 | apolipoprotein B mRNA editing enzyme catalytic subunit 1 | tumor-suppressor | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1085 | C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both thetype II transcript and apobec-1, the catalytic subunit of the apolipoprotein BmRNA-editing enzyme. | Mukhopadhyay D | Am J Hum Genet | [details] | 11727199 | S0002-9297(07)61281-6 |