Summary:

NameOvarian and breast cancer (A:m1A)
DescriptionCSF-1 expression is increased by the overexpression of ALKBH3. This results in cancer cell invasiveness without affecting cell proliferation and migration
Related RNA reactionA:m1A
Found in RNAmRNA
Modified TranscriptCSF-1
Mapping Technologym1A-MAP, MeRIP-seq
Quantification techniquesqRT-PCR, IP-qRT-PCR

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
ALKBH3 alkB homolog 3, alpha-ketoglutarate dependent dioxygenase oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1102 Human ALKBH3-induced m(1)A demethylation increases the CSF-1 mRNA stability inbreast and ovarian cancer cells. Woo HH Biochim Biophys Acta Gene Regul Mech [details] 30342176 S1874-9399(18)30274-8

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